Assessment of Structural Intolerance and Durability
General Structure Information 2yud YTHDC1 solution structure of the yth domain in yth domain- containing protein 1 (putative splicing factor yt521) -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TARADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTHTITL 2 DOMAIN-CONTAINING PROTEIN 1 (PUTATIVE SPLICINGTITL 3 FACTOR YT521)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 1yzg ARL5B structure of human adp-ribosylation factor-like 8 2.0Å AUTH A.ATANASSOVA,J.CHOE,C.ARROWSMITH,A.EDWARDS,AUTH 2 M.SUNDSTROM,A.BOCHKAREV,H.PARKTITL STRUCTURE OF HUMAN ADP-RIBOSYLATION FACTOR-LIKE 8REF TO BE PUBLISHED 2005REFN Variant Set Distributions Mapped Variants
General Structure Information 3tht ALKBH8 crystal structure and rna binding properties of the rrm/alkb domains in human abh8, an enzyme catalyzing trna hypermodification, northeast structural genomics consortium target hr5601b 3.01Å AUTH C.PASTORE,I.TOPALIDOU,F.FOROUHAR,A.C.YAN,M.LEVY,J.F.HUNTTITL CRYSTAL STRUCTURE AND RNA BINDING PROPERTIES OF THE RNATITL 2 RECOGNITION MOTIF (RRM) AND ALKB DOMAINS IN HUMAN ALKBTITL 3 HOMOLOG 8 (ABH8), […]
General Structure Information 2lmd PROX1 minimal constraints solution nmr structure of prospero homeobox protein 1 from homo sapiens, northeast structural genomics consortium target hr4660b -1.0Å AUTH O.F.LANGE,P.ROSSI,N.G.SGOURAKIS,Y.SONG,H.W.LEE,J.M.ARAMINI,AUTH 2 A.ERTEKIN,R.XIAO,T.B.ACTON,G.T.MONTELIONE,D.BAKERTITL DETERMINATION OF SOLUTION STRUCTURES OF PROTEINS UP TO 40TITL 2 KDA USING CS-ROSETTA WITH SPARSE NMR DATA FROM DEUTERATEDTITL 3 SAMPLES.REF PROC.NATL.ACAD.SCI.USA V. 109 10873 2012REFN […]
General Structure Information 3bl7 DCPS synthetic gene encoded dcps bound to inhibitor dg156844 2.31Å AUTH J.SINGH,M.SALCIUS,S.W.LIU,B.L.STAKER,R.MISHRA,AUTH 2 J.THURMOND,G.MICHAUD,D.R.MATTOON,J.PRINTEN,AUTH 3 J.CHRISTENSEN,J.M.BJORNSSON,B.A.POLLOK,M.KILEDJIAN,AUTH 4 L.STEWART,J.JARECKI,M.E.GURNEYTITL DCPS AS A THERAPEUTIC TARGET FOR SPINAL MUSCULARTITL 2 ATROPHY.REF ACS CHEM.BIOL. V. 3 711 2008REFN ISSN 1554-8929PMID 18839960DOI 10.1021/CB800120T Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2gw6 TSEN15 nmr structure of the human trna endonuclease sen15 subunit -1.0Å AUTH J.SONG,J.L.MARKLEYTITL THREE-DIMENSIONAL STRUCTURE DETERMINED FOR ATITL 2 SUBUNIT OF HUMAN TRNA SPLICING ENDONUCLEASETITL 3 (SEN15) REVEALS A NOVEL DIMERIC FOLD.REF J.MOL.BIOL. V. 366 155 2007REFN ISSN 0022-2836PMID 17166513DOI 10.1016/J.JMB.2006.11.024 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1twq PGLYRP3 crystal structure of the c-terminal pgn-binding domain of human pgrp- ialpha in complex with pgn analog muramyl tripeptide 2.3Å AUTH R.GUAN,A.ROYCHOWDHURY,B.EMBER,S.KUMAR,G.-A.BOONS,AUTH 2 R.A.MARIUZZATITL STRUCTURAL BASIS FOR PEPTIDOGLYCAN BINDING BY PEPTIDOGLYCANTITL 2 RECOGNITION PROTEINSREF PROC.NATL.ACAD.SCI.USA V. 101 17168 2004REFN ISSN 0027-8424PMID 15572450DOI 10.1073/PNAS.0407856101 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3c9q WDYHV1 crystal structure of the uncharacterized human protein c8orf32 with bound peptide 1.5Å AUTH E.BITTO,C.A.BINGMAN,J.G.MCCOY,G.E.WESENBERG,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF THE UNCHARACTERIZED HUMAN PROTEINTITL 2 C8ORF32 WITH BOUND PEPTIDE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2bei SAT2 x-ray structure of thialysine n-acetyltransferase (ssat2) from homo sapiens 1.84Å AUTH B.W.HAN,C.A.BINGMAN,G.E.WESENBERG,G.N.PHILLIPSTITL CRYSTAL STRUCTURE OF HOMO SAPIENS THIALYSINETITL 2 NEPSILON-ACETYLTRANSFERASE (HSSSAT2) IN COMPLEXTITL 3 WITH ACETYL COENZYME A.REF PROTEINS V. 64 288 2006REFN ISSN 0887-3585PMID 16596569DOI 10.1002/PROT.20967 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3fdw SYTL4 crystal structure of a c2 domain from human synaptotagmin- like protein 4 2.2Å AUTH J.B.BONANNO,M.RUTTER,K.T.BAIN,S.MILLER,R.ROMERO,AUTH 2 S.WASSERMAN,J.M.SAUDER,S.K.BURLEY,S.C.ALMOTITL CRYSTAL STRUCTURE OF A C2 DOMAIN FROM HUMANTITL 2 SYNAPTOTAGMIN-LIKE PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants