General Structure Information
| PDB ID | 2lmd |
| HGNC Gene Label(s) | PROX1 |
| Structure Name | minimal constraints solution nmr structure of prospero homeobox protein 1 from homo sapiens, northeast structural genomics consortium target hr4660b |
| Resolution | -1.0Å |
| Reference | AUTH O.F.LANGE,P.ROSSI,N.G.SGOURAKIS,Y.SONG,H.W.LEE,J.M.ARAMINI,AUTH 2 A.ERTEKIN,R.XIAO,T.B.ACTON,G.T.MONTELIONE,D.BAKERTITL DETERMINATION OF SOLUTION STRUCTURES OF PROTEINS UP TO 40TITL 2 KDA USING CS-ROSETTA WITH SPARSE NMR DATA FROM DEUTERATEDTITL 3 SAMPLES.REF PROC.NATL.ACAD.SCI.USA V. 109 10873 2012REFN ISSN 0027-8424PMID 22733734DOI 10.1073/PNAS.1203013109 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 163 |
| Number Of SNVs | 13 |
| Number Of Permutations | 6909 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.051 |
| p-value | 0.903 |
COSMIC
| Number Of Residues | 163 |
| Number Of SNVs | 6 |
| Number Of Permutations | 478 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.067 |
| p-value | 0.699 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 13 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.067 |
| p-value | 0.756 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
