General Structure Information
| PDB ID | 2yud |
| HGNC Gene Label(s) | YTHDC1 |
| Structure Name | solution structure of the yth domain in yth domain- containing protein 1 (putative splicing factor yt521) |
| Resolution | -1.0Å |
| Reference | AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TARADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTHTITL 2 DOMAIN-CONTAINING PROTEIN 1 (PUTATIVE SPLICINGTITL 3 FACTOR YT521)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 173 |
| Number Of SNVs | 21 |
| Number Of Permutations | 4285 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.029 |
| p-value | 0.829 |
COSMIC
| Number Of Residues | 173 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.333 |
| p-value | 0.049 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 21 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.319 |
| p-value | 0.228 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
