Assessment of Structural Intolerance and Durability
General Structure Information 1yxm PECR crystal structure of peroxisomal trans 2-enoyl coa reductase 1.9Å AUTH A.JANSSON,S.NG,C.ARROWSMITH,S.SHARMA,A.M.EDWARDS,AUTH 2 F.VON DELFT,M.SUNDSTROM,U.OPPERMANNTITL CRYSTAL STRUCTURE OF PERIXOMAL TRANS 2-ENOYL COATITL 2 REDUCTASE (PECRA)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2enp SYT17 solution structure of the first c2 domain from human b/k protein -1.0Å AUTH H.ENDO,T.NAGASHIMA,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN FROMTITL 2 HUMAN B/K PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2e6s UHRF2 solution structure of the phd domain in ring finger protein 107 -1.0Å AUTH S.KADIRVEL,F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,AUTH 2 T.TERADA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PHD DOMAIN IN RINGTITL 2 FINGER PROTEIN 107REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1yde HSD17B14 crystal structure of human retinal short-chain dehydrogenase/reductase 3 2.4Å AUTH P.LUKACIK,B.KELLER,G.BUNKOCZI,K.L.KAVANAGH,K.KAVANAGH,AUTH 2 W.H.LEE,W.HWA LEE,J.ADAMSKI,U.OPPERMANNTITL STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF HUMAN ORPHANTITL 2 DHRS10 REVEALS A NOVEL CYTOSOLIC ENZYME WITH STEROIDTITL 3 DEHYDROGENASE ACTIVITY.REF BIOCHEM.J. V. 402 419 2007REFN ISSN 0264-6021PMID 17067289DOI 10.1042/BJ20061319 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3k1z HDHD3 crystal structure of human haloacid dehalogenase-like hydrolase domain containing 3 (hdhd3) 1.55Å AUTH E.UGOCHUKWU,K.GUO,W.W.YUE,E.PILKA,K.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN HALOACID DEHALOGENASE-LIKETITL 2 HYDROLASE DOMAIN CONTAINING 3 (HDHD3)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2k2c RCHY1 solution nmr structure of n-terminal domain of human pirh2. northeast structural genomics consortium (nesg) target ht2a -1.0Å AUTH Y.SHENG,R.C.LAISTER,A.LEMAK,B.WU,E.TAI,S.DUAN,AUTH 2 J.LUKIN,M.SUNNERHAGEN,S.SRISAILAM,M.KARRA,AUTH 3 S.BENCHIMOL,C.H.ARROWSMITHTITL MOLECULAR BASIS OF PIRH2-MEDIATED P53TITL 2 UBIQUITYLATION.REF NAT.STRUCT.MOL.BIOL. V. 15 1334 2008REFN ISSN 1545-9993PMID 19043414DOI 10.1038/NSMB.1521 Variant Set Distributions Mapped Variants
General Structure Information 2pqf PARP12 human poly(adp-ribose) polymerase 12, catalytic fragment in complex with an inhibitor 3-aminobenzoic acid 2.2Å AUTH T.KARLBERG,M.KLEPSCH,A.G.THORSELL,C.D.ANDERSSON,A.LINUSSON,AUTH 2 H.SCHULERTITL STRUCTURAL BASIS FOR LACK OF ADP-RIBOSYLTRANSFERASE ACTIVITYTITL 2 IN POLY(ADP-RIBOSE) POLYMERASE-13/ZINC FINGER ANTIVIRALTITL 3 PROTEIN.REF J.BIOL.CHEM. V. 290 7336 2015REFN ISSN 0021-9258PMID 25635049DOI 10.1074/JBC.M114.630160 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 1wyn CNN2 solution structure of the ch domain of human calponin-2 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN OF HUMANTITL 2 CALPONIN-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2djr ZBED2 solution structures of the c2h2 type zinc finger domain of human zinc finger bed domain containing protein 2 -1.0Å AUTH M.SATO,A.SASAGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C2H2 TYPE ZINC FINGERTITL 2 DOMAIN OF HUMAN ZINC FINGER BED DOMAIN CONTAININGTITL 3 PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 2yu4 NSMCE2 solution structure of the sp-ring domain in non-smc element 2 homolog (mms21, s. cerevisiae) -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TARADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SP-RING DOMAIN INTITL 2 NON-SMC ELEMENT 2 HOMOLOG (MMS21, S. CEREVISIAE)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants