Assessment of Structural Intolerance and Durability
General Structure Information 3fe4 CA6 crystal structure of human carbonic anhydrase vi 1.9Å AUTH E.S.PILKA,G.KOCHAN,U.OPPERMANN,W.W.YUETITL CRYSTAL STRUCTURE OF THE SECRETORY ISOZYME OF MAMMALIANTITL 2 CARBONIC ANHYDRASES CA VI: IMPLICATIONS FOR BIOLOGICALTITL 3 ASSEMBLY AND INHIBITOR DEVELOPMENTREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 419 485 2012REFN ISSN 0006-291XPMID 22366092DOI 10.1016/J.BBRC.2012.02.038 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3umn LMNB1 crystal structure of lamin-b1 2.0Å AUTH J.RUAN,C.XU,C.BIAN,R.LAM,J.P.WANG,J.KANIA,J.MIN,J.ZANGTITL CRYSTAL STRUCTURES OF THE COIL 2B FRAGMENT AND THE GLOBULARTITL 2 TAIL DOMAIN OF HUMAN LAMIN B1.REF FEBS LETT. V. 586 314 2012REFN ISSN 0014-5793PMID 22265972DOI 10.1016/J.FEBSLET.2012.01.007 Variant Set Distributions Mapped Variants
General Structure Information 2vph PTPN4 crystal structure of the human protein tyrosine phosphatase, non-receptor type 4, pdz domain 1.9Å AUTH A.K.ROOS,J.WANG,N.BURGESS-BROWN,J.M.ELKINS,K.KAVANAGH,AUTH 2 A.C.W.PIKE,P.FILIPPAKOPOULOS,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,F.VON DELFT,C.BOUNTRA,S.KNAPPTITL CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINETITL 2 PHOSPHATASE, NON-RECEPTOR TYPE 4, PDZ DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2he9 NKTR structure of the peptidylprolyl isomerase domain of the human nk-tumour recognition protein 2.0Å AUTH T.DAVIS,J.R.WALKER,E.M.NEWMAN,F.MACKENZIE,AUTH 2 C.BUTLER-COLE,P.J.FINERTY JR.,J.WEIGELT,AUTH 3 M.SUNDSTROM,C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 4 S.DHE-PAGANONTITL STRUCTURE OF THE PPIASE CYCLOPHILIN-TYPE DOMAIN OFTITL 2 THE HUMAN NK-TUMOR RECOGNITION PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x5z PTPRD solution structure of the fibronectin type-iii domain of human protein tyrosine phosphatase, receptor type, d isoform 4 variant -1.0Å AUTH M.YONEYAMA,K.SAITO,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIBRONECTIN TYPE-IIITITL 2 DOMAIN OF HUMAN PROTEIN TYROSINE PHOSPHATASE,TITL 3 RECEPTOR TYPE, D ISOFORM 4 VARIANTREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s […]
General Structure Information 2k7p FLNA filamin a ig-like domains 16-17 -1.0Å AUTH O.K.HEIKKINEN,S.RUSKAMO,P.V.KONAREV,D.I.SVERGUN,AUTH 2 T.IIVANAINEN,S.M.HEIKKINEN,P.PERMI,H.KOSKELA,AUTH 3 I.KILPELAINEN,J.YLANNETITL ATOMIC STRUCTURES OF TWO NOVEL IMMUNOGLOBULIN-LIKETITL 2 DOMAIN PAIRS IN THE ACTIN CROSS-LINKING PROTEINTITL 3 FILAMINREF J.BIOL.CHEM. V. 284 25450 2009REFN ISSN 0021-9258PMID 19622754DOI 10.1074/JBC.M109.019661 Variant Set Distributions Mapped Variants
General Structure Information 3tyy LMNB1 crystal structure of human lamin-b1 coil 2 segment 2.4Å AUTH J.RUAN,C.XU,C.BIAN,R.LAM,J.P.WANG,J.KANIA,J.MIN,J.ZANGTITL CRYSTAL STRUCTURES OF THE COIL 2B FRAGMENT AND THE GLOBULARTITL 2 TAIL DOMAIN OF HUMAN LAMIN B1.REF FEBS LETT. V. 586 314 2012REFN ISSN 0014-5793PMID 22265972DOI 10.1016/J.FEBSLET.2012.01.007 Variant Set Distributions Mapped Variants
General Structure Information 2pa2 RPL10 crystal structure of human ribosomal protein l10 core domain 2.5Å AUTH M.NISHIMURA,T.KAMINISHI,C.TAKEMOTO,M.KAWAZOE,AUTH 2 T.YOSHIDA,A.TANAKA,S.SUGANO,M.SHIROUZU,T.OHKUBO,AUTH 3 S.YOKOYAMA,Y.KOBAYASHITITL CRYSTAL STRUCTURE OF HUMAN RIBOSOMAL PROTEIN L10TITL 2 CORE DOMAIN REVEALS EUKARYOTE-SPECIFIC MOTIFS INTITL 3 ADDITION TO THE CONSERVED FOLDREF J.MOL.BIOL. V. 377 421 2008REFN ISSN 0022-2836PMID 18258260DOI 10.1016/J.JMB.2008.01.003 Variant Set Distributions Mapped Variants
General Structure Information 2jjd PTPRE protein tyrosine phosphatase, receptor type, e isoform 3.2Å AUTH A.J.BARR,E.UGOCHUKWU,W.H.LEE,O.N.F.KING,P.FILIPPAKOPOULOS,AUTH 2 I.ALFANO,P.SAVITSKY,N.A.BURGESS-BROWN,S.MULLER,S.KNAPPTITL LARGE-SCALE STRUCTURAL ANALYSIS OF THE CLASSICAL HUMANTITL 2 PROTEIN TYROSINE PHOSPHATOME.REF CELL(CAMBRIDGE,MASS.) V. 136 352 2009REFN ISSN 0092-8674PMID 19167335DOI 10.1016/J.CELL.2008.11.038 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants