General Structure Information
| PDB ID | 3fe4 |
| HGNC Gene Label(s) | CA6 |
| Structure Name | crystal structure of human carbonic anhydrase vi |
| Resolution | 1.9Å |
| Reference | AUTH E.S.PILKA,G.KOCHAN,U.OPPERMANN,W.W.YUETITL CRYSTAL STRUCTURE OF THE SECRETORY ISOZYME OF MAMMALIANTITL 2 CARBONIC ANHYDRASES CA VI: IMPLICATIONS FOR BIOLOGICALTITL 3 ASSEMBLY AND INHIBITOR DEVELOPMENTREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 419 485 2012REFN ISSN 0006-291XPMID 22366092DOI 10.1016/J.BBRC.2012.02.038 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 245 |
| Number Of SNVs | 62 |
| Number Of Permutations | 18912 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.049 |
| p-value | 0.84 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 62 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.296 |
| p-value | 0.571 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
