Assessment of Structural Intolerance and Durability
General Structure Information 1zrh HS3ST1 crystal structure of human heparan sulfate glucosamine 3-o- sulfotransferase 1 in complex with pap 2.1Å AUTH A.DONG,L.DOMBROVSKI,P.LOPPNAU,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 A.N.PLOTNIKOVTITL CRYSTAL STRUCTURE OF HUMAN HEPARAN SULFATETITL 2 GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 IN COMPLEX WITHTITL 3 PAPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 1jbi COCH nmr structure of the lccl domain -1.0Å AUTH E.LIEPINSH,M.TREXLER,A.KAIKKONEN,J.WEIGELT,AUTH 2 L.BANYAI,L.PATTHY,G.OTTINGTITL NMR STRUCTURE OF THE LCCL DOMAIN AND IMPLICATIONSTITL 2 FOR DFNA9 DEAFNESS DISORDER.REF EMBO J. V. 20 5347 2001REFN ISSN 0261-4189PMID 11574466DOI 10.1093/EMBOJ/20.19.5347 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3bfx SULT1C2 crystal structure of human sulfotransferase sult1c1 in complex with pap 1.8Å AUTH L.DOMBROVSKI,A.DONG,A.BOCHKAREV,A.N.PLOTNIKOVTITL CRYSTAL STRUCTURES OF HUMAN SULFOTRANSFERASESTITL 2 SULT1B1 AND SULT1C1 COMPLEXED WITH THE COFACTORTITL 3 PRODUCT ADENOSINE-3-5-DIPHOSPHATE (PAP).REF PROTEINS V. 64 1091 2006REFN ISSN 0887-3585PMID 16804942DOI 10.1002/PROT.21048 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 3epp RNMT crystal structure of mrna cap guanine-n7 methyltransferase (rnmt) in complex with sinefungin 2.41Å AUTH H.ZENG,M.F.AMAYA,P.LOPPNAU,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOTCHKAREV,J.MIN,A.N.PLOTNIKOV,AUTH 3 H.WUTITL CRYSTAL STRUCTURE OF MRNA CAP GUANINE-N7 METHYLTRANSFERASETITL 2 (RNMT) IN COMPLEX WITH SINEFUNGIN.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ooq PTPRT crystal structure of the human receptor phosphatase ptprt 1.8Å AUTH A.J.BARR,E.UGOCHUKWU,W.H.LEE,O.N.KING,P.FILIPPAKOPOULOS,AUTH 2 I.ALFANO,P.SAVITSKY,N.A.BURGESS-BROWN,S.MULLER,S.KNAPPTITL LARGE-SCALE STRUCTURAL ANALYSIS OF THE CLASSICAL HUMANTITL 2 PROTEIN TYROSINE PHOSPHATOME.REF CELL(CAMBRIDGE,MASS.) V. 136 352 2009REFN ISSN 0092-8674PMID 19167335DOI 10.1016/J.CELL.2008.11.038 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1wie RIMBP2 solution structure of the first sh3 domain of kiaa0318 protein -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST SH3 DOMAIN OFTITL 2 KIAA0318 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2kkr ATXN7 solution structure of sca7 zinc finger domain from human ataxin-7 protein -1.0Å AUTH J.BONNET,Y.WANG,A.ATKINSON,J.KOFFLER,C.ROMIER,A.HAMICHE,AUTH 2 L.TORA,D.DEVYS,B.KIEFFERTITL HISTONE DEUBIQUITINATION BY SAGA IS MODULATED BY ANTITL 2 ATYPICAL ZINC FINGER DOMAIN OF ATAXIN-7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wh8 CUX2 solution structure of the third cut domain of human homeobox protein cux-2 -1.0Å AUTH N.NAMEKI,N.TOCHIO,S.KOSHIBA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD CUT DOMAIN OFTITL 2 HUMAN HOMEOBOX PROTEIN CUX-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ebz RGS12 solution structure of the rgs domain from human regulator of g-protein signaling 12 (rgs12) -1.0Å AUTH H.P.ZHANG,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RGS DOMAIN FROM HUMANTITL 2 REGULATOR OF G-PROTEIN SIGNALING 12 (RGS12)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wjm SPTBN2 solution structure of pleckstrin homology domain of human beta iii spectrin. -1.0Å AUTH M.SATO,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF PLECKSTRIN HOMOLOGY DOMAINTITL 2 OF HUMAN BETA III SPECTRINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants