1ZRH.A | HS3ST1

General Structure Information

PDB ID 1zrh
HGNC Gene Label(s) HS3ST1
Structure Name crystal structure of human heparan sulfate glucosamine 3-o- sulfotransferase 1 in complex with pap
Resolution 2.1Å
Reference AUTH A.DONG,L.DOMBROVSKI,P.LOPPNAU,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 A.N.PLOTNIKOVTITL CRYSTAL STRUCTURE OF HUMAN HEPARAN SULFATETITL 2 GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 IN COMPLEX WITHTITL 3 PAPREF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 263
Number Of SNVs 83
Number Of Permutations 14711
Optimal Distance Threshold 13.0
K Statistic 0.113
p-value 0.207
COSMIC

Number Of Residues 263
Number Of SNVs 4
Number Of Permutations 90
Optimal Distance Threshold 17.0
K Statistic 0.333
p-value 0.853

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 83
Number Of COSMIC SNVs 3
Optimal Distance Threshold 17.0
K Statistic 0.448
p-value 0.568

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants