General Structure Information
| PDB ID | 1zrh |
| HGNC Gene Label(s) | HS3ST1 |
| Structure Name | crystal structure of human heparan sulfate glucosamine 3-o- sulfotransferase 1 in complex with pap |
| Resolution | 2.1Å |
| Reference | AUTH A.DONG,L.DOMBROVSKI,P.LOPPNAU,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 A.N.PLOTNIKOVTITL CRYSTAL STRUCTURE OF HUMAN HEPARAN SULFATETITL 2 GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 IN COMPLEX WITHTITL 3 PAPREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 263 |
| Number Of SNVs | 83 |
| Number Of Permutations | 14711 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.113 |
| p-value | 0.207 |
COSMIC
| Number Of Residues | 263 |
| Number Of SNVs | 4 |
| Number Of Permutations | 90 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.333 |
| p-value | 0.853 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 83 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.448 |
| p-value | 0.568 |