Assessment of Structural Intolerance and Durability
General Structure Information 1wwy TXNL1 solution structure of the duf1000 domain of a thioredoxin-like protein 1 -1.0Å AUTH A.K.GORONCY,S.KOSHIBA,N.TOCHIO,T.TOMIZAWA,M.INOUE,A.TANAKA,AUTH 2 S.SUGANO,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL DUF1000 DOMAIN OF THETITL 2 HUMAN THIOREDOXIN-LIKE 1 PROTEIN.REF PROTEINS V. 78 2176 2010REFN ISSN 0887-3585PMID 20455272DOI 10.1002/PROT.22719 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2d8k SYT7 solution structure of the first c2 domain of synaptotagmin vii -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OFTITL 2 SYNAPTOTAGMIN VIIREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1wx6 NCK2 solution structure of the sh3 domain of the human cytoplasmic protein nck2 -1.0Å AUTH S.OHNISHI,T.KIGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF THE HUMANTITL 2 CYTOPLASMIC PROTEIN NCK2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2p0r CAPN9 structure of human calpain 9 in complex with leupeptin 2.5Å AUTH T.L.DAVIS,R.PARAMANATHAN,J.R.WALKER,C.BUTLER-COLE,AUTH 2 P.J.FINERTY JR.,J.WEIGELT,M.SUNDSTROM,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL STRUCTURES OF HUMAN MINICALPAINS BOUND TO INHIBITORSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2csi RIMBP2 solution structure of the third sh3 domain of human rim- binding protein 2 -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD SH3 DOMAIN OFTITL 2 HUMAN RIM-BINDING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2czh IMPA2 crystal structure of human myo-inositol monophosphatase 2 (impa2) with phosphate ion (orthorhombic form) 2.7Å AUTH R.ARAI,K.ITO,T.OHNISHI,H.OHBA,R.AKASAKA,Y.BESSHO,AUTH 2 K.HANAWA-SUETSUGU,T.YOSHIKAWA,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF HUMAN MYO-INOSITOLTITL 2 MONOPHOSPHATASE 2, THE PRODUCT OF THE PUTATIVETITL 3 SUSCEPTIBILITY GENE FOR BIPOLAR DISORDER,TITL 4 SCHIZOPHRENIA, AND FEBRILE SEIZURESREF PROTEINS V. 67 732 2007REFN ISSN 0887-3585PMID 17340635DOI […]
General Structure Information 2q5e CTDSP2 crystal structure of human carboxy-terminal domain rna polymerase ii polypeptide a small phosphatase 2 2.51Å AUTH S.C.ALMO,J.B.BONANNO,J.M.SAUDER,S.EMTAGE,AUTH 2 T.P.DILORENZO,V.MALASHKEVICH,S.R.WASSERMAN,AUTH 3 S.SWAMINATHAN,S.ESWARAMOORTHY,R.AGARWAL,D.KUMARAN,AUTH 4 M.MADEGOWDA,S.RAGUMANI,Y.PATSKOVSKY,J.ALVARADO,AUTH 5 U.A.RAMAGOPAL,J.FABER-BARATA,M.R.CHANCE,A.SALI,AUTH 6 A.FISER,Z.Y.ZHANG,D.S.LAWRENCE,S.K.BURLEYTITL STRUCTURAL GENOMICS OF PROTEIN PHOSPHATASES.REF J.STRUCT.FUNCT.GENOM. V. 8 121 2007REFN ISSN 1345-711XPMID 18058037DOI 10.1007/S10969-007-9036-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2csq RIMBP2 solution structure of the second sh3 domain of human rim- binding protein 2 -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND SH3 DOMAIN OFTITL 2 HUMAN RIM-BINDING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dk7 TCERG1 solution structure of ww domain in transcription elongation regulator 1 -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF WW DOMAIN IN TRANSCRIPTIONTITL 2 ELONGATION REGULATOR 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x2l CUX2 solution structure of the cut domain of human homeobox protein cux-2 (cut-like 2) -1.0Å AUTH Y.O.KAMATARI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CUT DOMAIN OF HUMANTITL 2 HOMEOBOX PROTEIN CUX-2 (CUT-LIKE 2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants