Assessment of Structural Intolerance and Durability
General Structure Information 2f1z USP7 crystal structure of hausp 3.2Å AUTH M.HU,L.GU,M.LI,P.D.JEFFREY,W.GU,Y.SHITITL STRUCTURAL BASIS OF COMPETITIVE RECOGNITION OF P53TITL 2 AND MDM2 BY HAUSP/USP7: IMPLICATIONS FOR THETITL 3 REGULATION OF THE P53-MDM2 PATHWAY.REF PLOS BIOL. V. 4 E27 2006REFN ISSN 1544-9173PMID 16402859DOI 10.1371/JOURNAL.PBIO.0040027 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3whd CLEC4D c-type lectin, human mcl 2.29Å AUTH A.FURUKAWA,J.KAMISHIKIRYO,D.MORI,K.TOYONAGA,Y.OKABE,A.TOJI,AUTH 2 R.KANDA,Y.MIYAKE,T.OSE,S.YAMASAKI,K.MAENAKATITL STRUCTURAL ANALYSIS FOR GLYCOLIPID RECOGNITION BY THE C-TYPETITL 2 LECTINS MINCLE AND MCLREF PROC.NATL.ACAD.SCI.USA V. 110 17438 2013REFN ISSN 0027-8424PMID 24101491DOI 10.1073/PNAS.1312649110 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4lir NUP35 crystal structure of a nucleoporin 35kda (nup35) from homo sapiens at 2.46 a resolution 2.46Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL CRYSTAL STRUCTURE OF A NUCLEOPORIN 35KDA (NUP35) FROM HOMOTITL 2 SAPIENS AT 2.46 A RESOLUTIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 2dnz RBM23 solution structure of the second rna binding domain of rna binding motif protein 23 -1.0Å AUTH S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND RNA BINDINGTITL 2 DOMAIN OF RNA BINDING MOTIF PROTEIN 23REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4ndg APTX human aprataxin (aptx) bound to rna-dna and zn – adenosine vanadate transition state mimic complex 2.54Å AUTH P.TUMBALE,J.S.WILLIAMS,M.J.SCHELLENBERG,T.A.KUNKEL,AUTH 2 R.S.WILLIAMSTITL APRATAXIN RESOLVES ADENYLATED RNA-DNA JUNCTIONS TO MAINTAINTITL 2 GENOME INTEGRITY.REF NATURE V. 506 111 2013REFN ISSN 0028-0836PMID 24362567DOI 10.1038/NATURE12824 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ob9 MSL3 structure of the human msl3 chromo-barrel domain at 2.5 angstrom resolution 2.5Å AUTH S.A.MOORE,Y.FERHATOGLUTITL STRUCTURE OF THE HUMAN MSL3 CHROMO-BARREL DOMAIN AT 2.5TITL 2 ANGSTROM RESOLUTIONREF J.BIOL.CHEM. 2010REFN ESSN 1083-351X Variant Set Distributions Mapped Variants
General Structure Information 2d8s MARCH8 solution structure of the ring domain of the human cellular modulator of immune recognition protein -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING DOMAIN OF THE HUMANTITL 2 CELLULAR MODULATOR OF IMMUNE RECOGNITION PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 4jon CEP170 crystal structure of a centrosomal protein 170kda, transcript variant beta (cep170) from homo sapiens at 2.15 a resolution (psi community target, sundstrom) 2.15Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG)TITL CRYSTAL STRUCTURE OF A CENTROSOMAL PROTEIN 170KDA,TITL 2 TRANSCRIPT VARIANT BETA (CEP170) FROM HOMO SAPIENS AT 2.15 ATITL 3 RESOLUTION […]
General Structure Information 4kng RNF43 crystal structure of human lgr5-rspo1-rnf43 2.5Å AUTH P.H.CHEN,X.CHEN,Z.LIN,D.FANG,X.HETITL THE STRUCTURAL BASIS OF R-SPONDIN RECOGNITION BY LGR5 ANDTITL 2 RNF43.REF GENES DEV. V. 27 1345 2013REFN ISSN 0890-9369PMID 23756651DOI 10.1101/GAD.219915.113 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4lp5 AGER crystal structure of the full-length human rage extracellular domain (vc1c2 fragment) 3.8Å AUTH L.YATIME,G.R.ANDERSENTITL STRUCTURAL INSIGHTS INTO THE OLIGOMERIZATION MODE OF THETITL 2 HUMAN RECEPTOR FOR ADVANCED GLYCATION END-PRODUCTS.REF FEBS J. V. 280 6556 2013REFN ISSN 1742-464XPMID 24119142DOI 10.1111/FEBS.12556 Variant Set Distributions Mapped Variants