Assessment of Structural Intolerance and Durability
General Structure Information 4g8a LY96 crystal structure of human tlr4 polymorphic variant d299g and t399i in complex with md-2 and lps 2.4Å AUTH U.OHTO,N.YAMAKAWA,S.AKASHI-TAKAMURA,K.MIYAKE,T.SHIMIZUTITL STRUCTURAL ANALYSES OF HUMAN TOLL-LIKE RECEPTOR 4TITL 2 POLYMORPHISMS D299G AND T399IREF J.BIOL.CHEM. V. 287 40611 2012REFN ISSN 0021-9258PMID 23055527DOI 10.1074/JBC.M112.404608 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3ue2 PUF60 crystal structure of a rna binding domain of poly-u binding splicing factor 60kda (puf60) from homo sapiens at 1.23 a resolution 1.23Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGYTITL CRYSTAL STRUCTURE OF A RNA BINDING DOMAIN OF POLY-U BINDINGTITL 2 SPLICING FACTOR 60KDA (PUF60) FROM […]
General Structure Information 3wh2 CLEC4E human mincle in complex with citrate 1.3Å AUTH A.FURUKAWA,J.KAMISHIKIRYO,D.MORI,K.TOYONAGA,Y.OKABE,A.TOJI,AUTH 2 R.KANDA,Y.MIYAKE,T.OSE,S.YAMASAKI,K.MAENAKATITL STRUCTURAL ANALYSIS FOR GLYCOLIPID RECOGNITION BY THE C-TYPETITL 2 LECTINS MINCLE AND MCLREF PROC.NATL.ACAD.SCI.USA V. 110 17438 2013REFN ISSN 0027-8424PMID 24101491DOI 10.1073/PNAS.1312649110 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ek1 RBM12 crystal structure of rna-binding motif of human rna-binding protein 12 2.0Å AUTH IHSANAWATI,Y.BESSHO,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF RNA-BINDING MOTIF OF HUMANTITL 2 RNA-BINDING PROTEIN 12REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cpd A1CF solution structure of the rna recognition motif of human apobec-1 complementation factor, acf -1.0Å AUTH T.NAGATA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF OFTITL 2 HUMAN APOBEC-1 COMPLEMENTATION FACTOR, ACFREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3w3g TLR8 crystal structure of human tlr8 (unliganded form) 2.3Å AUTH H.TANJI,U.OHTO,T.SHIBATA,K.MIYAKE,T.SHIMIZUTITL STRUCTURAL REORGANIZATION OF THE TOLL-LIKE RECEPTOR 8 DIMERTITL 2 INDUCED BY AGONISTIC LIGANDSREF SCIENCE V. 339 1426 2013REFN ISSN 0036-8075PMID 23520111DOI 10.1126/SCIENCE.1229159 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4h5s CADM1 complex structure of necl-2 and crtam 1.7Å AUTH S.ZHANG,G.LU,J.QI,Y.LI,Z.ZHANG,B.ZHANG,Z.FAN,J.YAN,G.F.GAOTITL COMPETITION OF CELL ADHESION AND IMMUNE RECOGNITION:TITL 2 INSIGHTS INTO THE INTERACTION BETWEEN CRTAM AND NECTIN-LIKETITL 3 2REF STRUCTURE V. 21 2013REFN ISSN 0969-2126PMID 23871486DOI 10.1016/J.STR.2013.06.006 Variant Set Distributions Mapped Variants
General Structure Information 3b2d CD180 crystal structure of human rp105/md-1 complex 2.8Å AUTH U.OHTO,K.MIYAKE,T.SHIMIZUTITL CRYSTAL STRUCTURES OF MOUSE AND HUMAN RP105/MD-1 COMPLEXESTITL 2 REVEAL UNIQUE DIMER ORGANIZATION OF THE TOLL-LIKE RECEPTORTITL 3 FAMILY.REF J.MOL.BIOL. V. 413 815 2011REFN ISSN 0022-2836PMID 21959264DOI 10.1016/J.JMB.2011.09.020 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2cqd RBM38 solution structure of the rna recognition motif in rna- binding region containing protein 1 -1.0Å AUTH T.SOMEYA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF INTITL 2 RNA-BINDING REGION CONTAINING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4im6 NLRP1 lrr domain from human nlrp1 1.65Å Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants