General Structure Information
| PDB ID | 2f1z |
| HGNC Gene Label(s) | USP7 |
| Structure Name | crystal structure of hausp |
| Resolution | 3.2Å |
| Reference | AUTH M.HU,L.GU,M.LI,P.D.JEFFREY,W.GU,Y.SHITITL STRUCTURAL BASIS OF COMPETITIVE RECOGNITION OF P53TITL 2 AND MDM2 BY HAUSP/USP7: IMPLICATIONS FOR THETITL 3 REGULATION OF THE P53-MDM2 PATHWAY.REF PLOS BIOL. V. 4 E27 2006REFN ISSN 1544-9173PMID 16402859DOI 10.1371/JOURNAL.PBIO.0040027 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 481 |
| Number Of SNVs | 40 |
| Number Of Permutations | 12304 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.04 |
| p-value | 0.743 |
COSMIC
| Number Of Residues | 481 |
| Number Of SNVs | 10 |
| Number Of Permutations | 5145 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.089 |
| p-value | 0.033 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 40 |
| Number Of COSMIC SNVs | 10 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.12 |
| p-value | 0.169 |