Assessment of Structural Intolerance and Durability
General Structure Information 1wfv MAGI2 solution structure of the fifth pdz domain of human membrane associated guanylate kinase inverted-2 (kiaa0705 protein) -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH PDZ DOMAIN OFTITL 2 HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASETITL 3 INVERTED-2 (KIAA0705 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1r03 FTMT crystal structure of a human mitochondrial ferritin 1.7Å AUTH B.LANGLOIS DESTAINTOT,P.SANTAMBROGIO,T.GRANIER,B.GALLOIS,AUTH 2 J.M.CHEVALLIER,G.PRECIGOUX,S.LEVI,P.AROSIOTITL CRYSTAL STRUCTURE AND BIOCHEMICAL PROPERTIES OF THE HUMANTITL 2 MITOCHONDRIAL FERRITIN AND ITS MUTANT SER144ALAREF J.MOL.BIOL. V. 340 277 2004REFN ISSN 0022-2836PMID 15201052DOI 10.1016/J.JMB.2004.04.036 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2css RIMS1 solution structure of the pdz domain of human kiaa0340 protein -1.0Å AUTH K.INOUE,X.-R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN OF HUMANTITL 2 KIAA0340 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2w18 PALB2 crystal structure of the c-terminal wd40 domain of human palb2 1.9Å AUTH A.W.OLIVER,S.SWIFT,C.J.LORD,A.ASHWORTH,L.H.PEARLTITL STRUCTURAL BASIS FOR RECRUITMENT OF BRCA2 BY PALB2REF EMBO REP. V. 10 990 2009REFN ISSN 1469-221XPMID 19609323DOI 10.1038/EMBOR.2009.126 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1uep MAGI2 solution structure of the third pdz domain of human atrophin-1 interacting protein 1 (kiaa0705 protein) -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD PDZ DOMAIN OFTITL 2 HUMAN ATROPHIN-1 INTERACTING PROTEIN 1 (KIAA0705TITL 3 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3gge GIPC2 crystal structure of the pdz domain of pdz domain-containing protein gipc2 2.6Å AUTH A.CHAIKUAD,V.HOZJAN,W.YUE,C.COOPER,J.ELKINS,A.C.W.PIKE,AUTH 2 A.K.ROOS,P.FILIPPAKOPOULOS,F.VON DELFT,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,J.WEIGELT,C.BOUNTRA,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PDZ DOMAIN-CONTAININGTITL 2 PROTEIN GIPC2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dip ZSWIM2 solution structure of the zz domain of zinc finger swim domain containing protein 2 -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZZ DOMAIN OF ZINC FINGERTITL 2 SWIM DOMAIN CONTAINING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2vwr LNX2 crystal structure of the second pdz domain of numb-binding protein 2 1.3Å AUTH A.K.ROOS,K.GUO,N.BURGESS-BROWN,W.W.YUE,J.M.ELKINS,AUTH 2 A.C.W.PIKE,P.FILIPPAKOPOULOS,C.H.ARROWSMITH,AUTH 3 M.WIKSTOM,A.EDWARDS,F.VON DELFT,C.BOUNTRA,D.DOYLE,AUTH 4 U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF THETITL 2 HUMAN NUMB-BINDING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kiv ANKS1B aida-1 sam domain tandem -1.0Å AUTH A.KURABI,S.BRENER,M.MOBLI,J.J.KWAN,L.W.DONALDSONTITL A NUCLEAR LOCALIZATION SIGNAL AT THE SAM-SAM DOMAINTITL 2 INTERFACE OF AIDA-1 SUGGESTS A REQUIREMENT FORTITL 3 DOMAIN UNCOUPLING PRIOR TO NUCLEAR IMPORT.REF J.MOL.BIOL. V. 392 1168 2009REFN ISSN 0022-2836PMID 19666031DOI 10.1016/J.JMB.2009.08.004 Variant Set Distributions Mapped Variants
General Structure Information 2eoh ZFP28 solution structure of the c2h2 type zinc finger (region 780- 812) of human zinc finger protein 28 homolog -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 780-812) OF HUMAN ZINC FINGER PROTEIN 28TITL 3 HOMOLOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants