Assessment of Structural Intolerance and Durability
General Structure Information 2xvs TTC5 crystal structure of human ttc5 (strap) c-terminal ob domain 1.8Å AUTH C.J.ADAMS,A.C.PIKE,S.MANIAM,T.D.SHARPE,A.S.COUTTS,S.KNAPP,AUTH 2 N.B.LA THANGUE,A.N.BULLOCKTITL THE P53 COFACTOR STRAP EXHIBITS AN UNEXPECTED TPR MOTIF ANDTITL 2 OLIGONUCLEOTIDE-BINDING (OB)-FOLD STRUCTURE.REF PROC.NATL.ACAD.SCI.USA V. 109 3778 2012REFN ISSN 0027-8424PMID 22362889DOI 10.1073/PNAS.1113731109 Variant Set Distributions Mapped Variants
General Structure Information 2em3 ZFP28 solution structure of the c2h2 type zinc finger (region 640- 672) of human zinc finger protein 28 homolog -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 640-672) OF HUMAN ZINC FINGER PROTEIN 28TITL 3 HOMOLOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3dh1 ADAT2 crystal structure of human trna-specific adenosine-34 deaminase subunit adat2 2.8Å AUTH M.WELIN,L.TRESAUGUES,J.ANDERSSON,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTENYOVA,L.LEHTIO,M.MOCHE,M.E.NILSSON,T.NYMAN,K.OLESEN,AUTH 5 C.PERSSON,J.SAGEMARK,H.SCHUELER,A.G.THORSELL,S.VAN DER BERG,AUTH 6 M.WISNIEWSKA,M.WIKSTROM,P.NORDLUNDTITL CRYSTAL STRUCTURE OF HUMAN TRNA-SPECIFIC ADENOSINE-34TITL 2 DEAMINASE SUBUNIT ADAT2.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2qgx UBE2Q1 ubiquitin-conjugating enzyme e2q 2.56Å AUTH Y.SHENG,J.H.HONG,R.DOHERTY,T.SRIKUMAR,J.SHLOUSH,AUTH 2 G.V.AVVAKUMOV,J.R.WALKER,S.XUE,D.NECULAI,J.W.WAN,S.K.KIM,AUTH 3 C.H.ARROWSMITH,B.RAUGHT,S.DHE-PAGANONTITL A HUMAN UBIQUITIN CONJUGATING ENZYME (E2)-HECT E3 LIGASETITL 2 STRUCTURE-FUNCTION SCREEN.REF MOL CELL PROTEOMICS V. 11 329 2012REFNPMID 22496338DOI 10.1074/MCP.O111.013706 Variant Set Distributions Mapped Variants
General Structure Information 2m38 ANKS1B ptb domain of aida1 -1.0Å AUTH L.DONALDSONTITL TO BE PUBLISHEDREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2epz ZFP28 solution structure of the 4th c2h2 type zinc finger domain of zinc finger protein 28 homolog -1.0Å AUTH K.FUTAMI,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 4TH C2H2 TYPE ZINCTITL 2 FINGER DOMAIN OF ZINC FINGER PROTEIN 28 HOMOLOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ehr INADL solution structure of the sixth pdz domain of human inad- like protein -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SIXTH PDZ DOMAIN OFTITL 2 HUMAN INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2xdv MINA crystal structure of the catalytic domain of flj14393 2.57Å AUTH R.CHOWDHURY,R.SEKIRNIK,N.C.BRISSETT,T.KROJER,C.-H.HO,S.S.NG,AUTH 2 I.J.CLIFTON,W.GE,N.J.KERSHAW,G.C.FOX,J.R.C.MUNIZ,M.VOLLMAR,AUTH 3 C.PHILLIPS,E.S.PILKA,K.L.KAVANAGH,F.VON DELFT,U.OPPERMANN ,AUTH 4 M.A.MCDONOUGH,A.J.DOHERTY,C.J.SCHOFIELDTITL RIBOSOMAL OXYGENASES ARE STRUCTURALLY CONSERVED FROMTITL 2 PROKARYOTES TO HUMANSREF NATURE V. 510 422 2014REFN ISSN 0028-0836PMID 24814345DOI 10.1038/NATURE13263 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3ph9 AGR3 crystal structure of the human anterior gradient protein 3 1.83Å AUTH V.D.NGUYEN,L.W.RUDDOCK,M.SALIN,R.K.WIERENGATITL CRYSTAL STRUCTURE OF THE HUMAN ANTERIOR GRADIENT PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2z0u WWC1 crystal structure of c2 domain of kibra protein 2.2Å AUTH K.MURAYAMA,M.KATO-MURAYAMA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF C2 DOMAIN OF KIBRA PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants