General Structure Information
| PDB ID | 2xdv |
| HGNC Gene Label(s) | MINA |
| Structure Name | crystal structure of the catalytic domain of flj14393 |
| Resolution | 2.57Å |
| Reference | AUTH R.CHOWDHURY,R.SEKIRNIK,N.C.BRISSETT,T.KROJER,C.-H.HO,S.S.NG,AUTH 2 I.J.CLIFTON,W.GE,N.J.KERSHAW,G.C.FOX,J.R.C.MUNIZ,M.VOLLMAR,AUTH 3 C.PHILLIPS,E.S.PILKA,K.L.KAVANAGH,F.VON DELFT,U.OPPERMANN ,AUTH 4 M.A.MCDONOUGH,A.J.DOHERTY,C.J.SCHOFIELDTITL RIBOSOMAL OXYGENASES ARE STRUCTURALLY CONSERVED FROMTITL 2 PROKARYOTES TO HUMANSREF NATURE V. 510 422 2014REFN ISSN 0028-0836PMID 24814345DOI 10.1038/NATURE13263 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 374 |
| Number Of SNVs | 106 |
| Number Of Permutations | 21143 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.01 |
| p-value | 0.85 |
COSMIC
| Number Of Residues | 374 |
| Number Of SNVs | 6 |
| Number Of Permutations | 3013 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.2 |
| p-value | 0.278 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 106 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.159 |
| p-value | 0.431 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
