Assessment of Structural Intolerance and Durability
General Structure Information 1ya0 SMG7 crystal structure of the n-terminal domain of human smg7 2.55Å AUTH N.FUKUHARA,J.EBERT,L.UNTERHOLZNER,D.LINDNER,AUTH 2 E.IZAURRALDE,E.CONTITITL SMG7 IS A 14-3-3-LIKE ADAPTOR IN THETITL 2 NONSENSE-MEDIATED MRNA DECAY PATHWAY.REF MOL.CELL V. 17 537 2005REFN ISSN 1097-2765PMID 15721257DOI 10.1016/J.MOLCEL.2005.01.010 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3nbh RMI2 crystal structure of human rmi1c-rmi2 complex 2.0Å AUTH F.WANG,Y.YANG,T.R.SINGH,V.BUSYGINA,R.GUO,K.WAN,W.WANG,AUTH 2 P.SUNG,A.R.MEETEI,M.LEITITL CRYSTAL STRUCTURES OF RMI1 AND RMI2, TWO OB-FOLD REGULATORYTITL 2 SUBUNITS OF THE BLM COMPLEX.REF STRUCTURE V. 18 1159 2010REFN ISSN 0969-2126PMID 20826342DOI 10.1016/J.STR.2010.06.008 Variant Set Distributions Mapped Variants
General Structure Information 4is7 CASKIN2 crystal structure of the caskin2 sam domain tandem 2.75Å AUTH KWAN J.J.,E.SMIRNOVA,V.SARIDAKIS,DONALDSON L.W.TITL CRYSTAL STRUCTURE OF THE CASKIN2 SAM DOMAIN TANDEMREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wwv CNKSR1 solution structure of the sam domain of human connector enhancer of ksr-like protein cnk1 -1.0Å AUTH A.GORONCY,T.KIGAWA,S.KOSHIBA,N.KOBAYASHI,N.TOCHIO,AUTH 2 M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SAM DOMAIN OF HUMANTITL 2 CONNECTOR ENHANCER OF KSR-LIKE PROTEIN CNK1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cp0 CLIP3 solution structure of the 1st cap-gly domain in human clip- 170-related protein clipr59 -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 1ST CAP-GLY DOMAIN INTITL 2 HUMAN CLIP-170-RELATED PROTEIN CLIPR59REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kxj UBXN4 solution structure of ubx domain of human ubxd2 protein -1.0Å AUTH Q.WU,H.HUANG,J.ZHANG,Q.HU,J.WU,Y.SHITITL SOLUTION STRCTURE OF UBX DOMAIN OF HUMAN UBXD2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fdw SYTL4 crystal structure of a c2 domain from human synaptotagmin- like protein 4 2.2Å AUTH J.B.BONANNO,M.RUTTER,K.T.BAIN,S.MILLER,R.ROMERO,AUTH 2 S.WASSERMAN,J.M.SAUDER,S.K.BURLEY,S.C.ALMOTITL CRYSTAL STRUCTURE OF A C2 DOMAIN FROM HUMANTITL 2 SYNAPTOTAGMIN-LIKE PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2xqq DYNLL2 human dynein light chain (dynll2) in complex with an in vitro evolved peptide (ac-srgtqte). 1.31Å AUTH P.RAPALI,L.RADNAI,D.SUVEGES,V.HARMAT,F.TOLGYESI,AUTH 2 W.Y.WAHLGREN,G.KATONA,L.NYITRAY,G.PALTITL DIRECTED EVOLUTION REVEALS THE BINDING MOTIF PREFERENCE OFTITL 2 THE LC8/DYNLL HUB PROTEIN AND PREDICTS LARGE NUMBERS OFTITL 3 NOVEL BINDERS IN THE HUMAN PROTEOMEREF PLOS ONE V. 6 18818 2011REFN […]
General Structure Information 2egm TRIM41 solution structure of the zf-b_box domain from human tripartite motif protein 41 -1.0Å AUTH K.INOUE,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-B_BOX DOMAIN FROMTITL 2 HUMAN TRIPARTITE MOTIF PROTEIN 41REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mxo PGAM5 crystal structure oh human phosphoglycerate mutase family member 5 (pgam5) 1.7Å AUTH A.CHAIKUAD,I.ALFANO,S.PICAUD,P.FILIPPAKOPOULOS,A.BARR,AUTH 2 F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,C.BOUNTRA,AUTH 3 K.TAKEDA,H.ICHIJO,S.KNAPPTITL CRYSTAL STRUCTURE OH HUMAN PHOSPHOGLYCERATE MUTASE FAMILYTITL 2 MEMBER 5 (PGAM5)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants