Assessment of Structural Intolerance and Durability
General Structure Information 3ldz STAM crystal structure of human stam1 vhs domain in complex with ubiquitin 2.6Å AUTH X.REN,J.H.HURLEYTITL VHS DOMAINS OF ESCRT-0 COOPERATE IN HIGH-AVIDITYTITL 2 BINDING TO POLYUBIQUITINATED CARGO.REF EMBO J. V. 29 1045 2010REFN ISSN 0261-4189PMID 20150893DOI 10.1038/EMBOJ.2010.6 Variant Set Distributions Mapped Variants
General Structure Information 2bei SAT2 x-ray structure of thialysine n-acetyltransferase (ssat2) from homo sapiens 1.84Å AUTH B.W.HAN,C.A.BINGMAN,G.E.WESENBERG,G.N.PHILLIPSTITL CRYSTAL STRUCTURE OF HOMO SAPIENS THIALYSINETITL 2 NEPSILON-ACETYLTRANSFERASE (HSSSAT2) IN COMPLEXTITL 3 WITH ACETYL COENZYME A.REF PROTEINS V. 64 288 2006REFN ISSN 0887-3585PMID 16596569DOI 10.1002/PROT.20967 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1y02 RFFL crystal structure of a fyve-type domain from caspase regulator carp2 1.8Å AUTH M.D.TIBBETTS,E.N.SHIOZAKI,L.GU,E.R.MCDONALD,AUTH 2 W.S.EL-DEIRY,Y.SHITITL CRYSTAL STRUCTURE OF A FYVE-TYPE ZINC FINGERTITL 2 DOMAIN FROM THE CASPASE REGULATOR CARP2.REF STRUCTURE V. 12 2257 2004REFN ISSN 0969-2126PMID 15576038DOI 10.1016/J.STR.2004.10.007 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3d3k EDC3 crystal structure of human edc3p 2.2Å AUTH S.H.M.LING,C.J.DECKER,M.A.WALSH,M.SHE,R.PARKER,H.SONGTITL CRYSTAL STRUCTURE OF HUMAN EDC3 AND ITS FUNCTIONALTITL 2 IMPLICATIONSREF MOL.CELL.BIOL. V. 28 5965 2008REFN ISSN 0270-7306PMID 18678652DOI 10.1128/MCB.00761-08 Variant Set Distributions Mapped Variants
General Structure Information 2eaq LMO7 crystal structure of pdz domain of kiaa0858 (lim), ms0793 from homo sapiens 1.46Å AUTH Y.XIE,S.KISHISHITA,K.MURAYAMA,C.TAKEMOTO,M.SHIROZU,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF PDZ DOMAIN OF KIAA0858 (LIM),TITL 2 MS0793 FROM HOMO SAPIENSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2a5j RAB2B crystal structure of human rab2b 1.5Å AUTH J.WANG,A.DONG,Y.SHEN,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 M.SUNDSTROM,A.BOCHKAREV,H.W.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB2BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yus SMARCC1 solution structure of the sant domain of human swi/snf- related matrix-associated actin-dependent regulator of chromatin subfamily c member 1 -1.0Å AUTH N.TOCHIO,S.KOSHIBA,K.SATIO,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SANT DOMAIN OF HUMANTITL 2 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENTTITL 3 REGULATOR OF CHROMATIN SUBFAMILY C MEMBER 1REF TO BE PUBLISHEDREFN Variant Set Distributions […]
General Structure Information 1x5h NEO1 the solution structure of the third fibronectin type iii domain of human neogenin -1.0Å AUTH N.TOCHIO,A.SASAGAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE THIRD FIBRONECTINTITL 2 TYPE III DOMAIN OF HUMAN NEOGENINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wxp THOC1 solution structure of the death domain of nuclear matrix protein p84 -1.0Å AUTH T.N.NIRAULA,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE DEATH DOMAIN OF NUCLEARTITL 2 MATRIX PROTEIN P84REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2o2o SH3KBP1 solution structure of domain b from human cin85 protein -1.0Å AUTH A.ABABOU,M.PFUHL,I.DIKIC,J.E.LADBURYTITL INVESTIGATION OF DOMAIN B FROM HUMAN CIN85TITL 2 PROTEIN: STRUCTURE, DYNAMICS AND PROLINE-RICHTITL 3 MOTIF BINDINGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants