Assessment of Structural Intolerance and Durability
General Structure Information 1ytq CRYBB2 structure of native human beta b2 crystallin 1.7Å AUTH M.A.SMITH,O.A.BATEMAN,R.JAENICKE,C.SLINGSBYTITL MUTATION OF INTERFACES IN DOMAIN-SWAPPED HUMANTITL 2 BETAB2-CRYSTALLINREF PROTEIN SCI. V. 16 615 2007REFN ISSN 0961-8368PMID 17327390DOI 10.1110/PS.062659107 Variant Set Distributions Mapped Variants
General Structure Information 2psr S100A7 human psoriasin (s100a7) ca2+ and zn2+ bound form (crystal form ii) 2.05Å AUTH D.E.BRODERSEN,J.NYBORG,M.KJELDGAARDTITL ZINC-BINDING SITE OF AN S100 PROTEIN REVEALED. TWO CRYSTALTITL 2 STRUCTURES OF CA2+-BOUND HUMAN PSORIASIN (S100A7) IN THETITL 3 ZN2+-LOADED AND ZN2+-FREE STATES.REF BIOCHEMISTRY V. 38 1695 1999REFN ISSN 0006-2960PMID 10026247DOI 10.1021/BI982483D Variant Set Distributions Ripley’s […]
General Structure Information 1f5n GBP1 human guanylate binding protein-1 in complex with the gtp analogue, gmppnp. 1.7Å AUTH B.PRAKASH,L.RENAULT,G.J.PRAEFCKE,C.HERRMANN,AUTH 2 A.WITTINGHOFERTITL TRIPHOSPHATE STRUCTURE OF GUANYLATE-BINDINGTITL 2 PROTEIN 1 AND IMPLICATIONS FOR NUCLEOTIDE BINDINGTITL 3 AND GTPASE MECHANISM.REF EMBO J. V. 19 4555 2000REFN ISSN 0261-4189PMID 10970849DOI 10.1093/EMBOJ/19.17.4555 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3pbl DRD3 structure of the human dopamine d3 receptor in complex with eticlopride 2.89Å AUTH E.Y.CHIEN,W.LIU,Q.ZHAO,V.KATRITCH,G.W.HAN,M.A.HANSON,L.SHI,AUTH 2 A.H.NEWMAN,J.A.JAVITCH,V.CHEREZOV,R.C.STEVENSTITL STRUCTURE OF THE HUMAN DOPAMINE D3 RECEPTOR IN COMPLEX WITHTITL 2 A D2/D3 SELECTIVE ANTAGONIST.REF SCIENCE V. 330 1091 2010REFN ISSN 0036-8075PMID 21097933DOI 10.1126/SCIENCE.1197410 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3npc MAPK9 crystal structure of jnk2 complexed with birb796 2.35Å AUTH A.KUGLSTATTER,M.GHATE,S.TSING,A.G.VILLASENOR,D.SHAW,AUTH 2 J.W.BARNETT,M.F.BROWNERTITL X-RAY CRYSTAL STRUCTURE OF JNK2 COMPLEXED WITH THE P38ALPHATITL 2 INHIBITOR BIRB796: INSIGHTS INTO THE RATIONAL DESIGN OFTITL 3 DFG-OUT BINDING MAP KINASE INHIBITORS.REF BIOORG.MED.CHEM.LETT. V. 20 5217 2010REFN ISSN 0960-894XPMID 20655210DOI 10.1016/J.BMCL.2010.06.157 Variant Set Distributions Ripley’s K […]
General Structure Information 1wym TAGLN2 solution structure of the ch domain of human transgelin-2 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN OF HUMANTITL 2 TRANSGELIN-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3zwh MYH9 ca2+-bound s100a4 c3s, c81s, c86s and f45w mutant complexed with myosin iia 1.94Å AUTH B.KISS,A.DUELLI,L.RADNAI,K.A.KEKESI,G.KATONA,L.NYITRAYTITL CRYSTAL STRUCTURE OF THE S100A4-NONMUSCLE MYOSIN IIA TAILTITL 2 FRAGMENT COMPLEX REVEALS AN ASYMMETRIC TARGET BINDINGTITL 3 MECHANISM.REF PROC.NATL.ACAD.SCI.USA V. 109 6048 2012REFN ISSN 0027-8424PMID 22460785DOI 10.1073/PNAS.1114732109 Variant Set Distributions Mapped Variants
General Structure Information 4n6h OPRD1 1.8 a structure of the human delta opioid 7tm receptor (psi community target) 1.8Å AUTH G.FENALTI,P.M.GIGUERE,V.KATRITCH,X.P.HUANG,A.A.THOMPSON,AUTH 2 V.CHEREZOV,B.L.ROTH,R.C.STEVENSTITL MOLECULAR CONTROL OF DELTA-OPIOID RECEPTOR SIGNALLING.REF NATURE V. 506 191 2014REFN ISSN 0028-0836PMID 24413399DOI 10.1038/NATURE12944 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2rop ATP7B solution structure of domains 3 and 4 of human atp7b -1.0Å AUTH L.BANCI,I.BERTINI,F.CANTINI,A.C.ROSENZWEIG,AUTH 2 L.A.YATSUNYKTITL METAL BINDING DOMAINS 3 AND 4 OF THE WILSONTITL 2 DISEASE PROTEIN: SOLUTION STRUCTURE ANDTITL 3 INTERACTION WITH THE COPPER(I) CHAPERONE HAH1REF BIOCHEMISTRY V. 47 7423 2008REFN ISSN 0006-2960PMID 18558714DOI 10.1021/BI8004736 Variant Set Distributions Mapped […]
General Structure Information 2d8n RCVRN crystal structure of human recoverin at 2.2 a resolution 2.2Å AUTH S.KAMO,S.KISHISHITA,K.MURAYAMA,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF HUMAN RECOVERIN AT 2.2 A RESOLUTIONREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants