General Structure Information
| PDB ID | 3pbl |
| HGNC Gene Label(s) | DRD3 |
| Structure Name | structure of the human dopamine d3 receptor in complex with eticlopride |
| Resolution | 2.89Å |
| Reference | AUTH E.Y.CHIEN,W.LIU,Q.ZHAO,V.KATRITCH,G.W.HAN,M.A.HANSON,L.SHI,AUTH 2 A.H.NEWMAN,J.A.JAVITCH,V.CHEREZOV,R.C.STEVENSTITL STRUCTURE OF THE HUMAN DOPAMINE D3 RECEPTOR IN COMPLEX WITHTITL 2 A D2/D3 SELECTIVE ANTAGONIST.REF SCIENCE V. 330 1091 2010REFN ISSN 0036-8075PMID 21097933DOI 10.1126/SCIENCE.1197410 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 263 |
| Number Of SNVs | 54 |
| Number Of Permutations | 10160 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.081 |
| p-value | 0.012 |
COSMIC
| Number Of Residues | 263 |
| Number Of SNVs | 3 |
| Number Of Permutations | 66 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 54 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.145 |
| p-value | 0.962 |