4N6H.A | OPRD1

General Structure Information

PDB ID 4n6h
HGNC Gene Label(s) OPRD1
Structure Name 1.8 a structure of the human delta opioid 7tm receptor (psi community target)
Resolution 1.8Å
Reference AUTH G.FENALTI,P.M.GIGUERE,V.KATRITCH,X.P.HUANG,A.A.THOMPSON,AUTH 2 V.CHEREZOV,B.L.ROTH,R.C.STEVENSTITL MOLECULAR CONTROL OF DELTA-OPIOID RECEPTOR SIGNALLING.REF NATURE V. 506 191 2014REFN ISSN 0028-0836PMID 24413399DOI 10.1038/NATURE12944

Variant Set Distributions

ExAC Variants

Number Of Residues 303
Number Of SNVs 66
Number Of Permutations 43388
Optimal Distance Threshold 9.0
K Statistic 0.038
p-value 0.684
COSMIC

Number Of Residues 303
Number Of SNVs 6
Number Of Permutations 1755
Optimal Distance Threshold 18.0
K Statistic 0.4
p-value 0.361

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 66
Number Of COSMIC SNVs 6
Optimal Distance Threshold 31.0
K Statistic 0.23
p-value 0.407

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants