Assessment of Structural Intolerance and Durability
General Structure Information 1wim RNF144A solution structure of the ring finger domain of the human ubcm4-interacting protein 4 -1.0Å AUTH K.MIYAMOTO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING FINGER DOMAIN OFTITL 2 THE HUMAN UBCM4-INTERACTING PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fby COMP the crystal structure of the signature domain of cartilage oligomeric matrix protein. 3.15Å AUTH K.TAN,M.DUQUETTE,A.JOACHIMIAK,J.LAWLERTITL THE CRYSTAL STRUCTURE OF THE SIGNATURE DOMAIN OF CARTILAGETITL 2 OLIGOMERIC MATRIX PROTEIN: IMPLICATIONS FOR COLLAGEN,TITL 3 GLYCOSAMINOGLYCAN AND INTEGRIN BINDING.REF FASEB J. V. 23 2490 2009REFN ISSN 0892-6638PMID 19276170DOI 10.1096/FJ.08-128090 Variant Set Distributions Ripley’s […]
General Structure Information 2rr8 IQGAP1 solution structure of calponin homology domain of iqgap1 -1.0Å AUTH R.UMEMOTO,N.NISHIDA,S.OGINO,I.SHIMADATITL NMR STRUCTURE OF THE CALPONIN HOMOLOGY DOMAIN OF HUMANTITL 2 IQGAP1 AND ITS IMPLICATIONS FOR THE ACTIN RECOGNITION MODE.REF J.BIOMOL.NMR V. 48 59 2010REFN ISSN 0925-2738PMID 20644981DOI 10.1007/S10858-010-9434-8 Variant Set Distributions Mapped Variants
General Structure Information 1qk9 MECP2 the solution structure of the domain from mecp2 that binds to methylated dna -1.0Å AUTH R.I.D.WAKEFIELD,B.O.SMITH,X.NAN,A.FREE,A.SOTERIOU,AUTH 2 D.UHRIN,A.P.BIRD,P.N.BARLOWTITL THE SOLUTION STRUCTURE OF THE DOMAIN FROM MECP2TITL 2 THAT BINDS TO METHYLATED DNAREF J.MOL.BIOL. V. 291 1055 1999REFN ISSN 0022-2836 70PMID 10518942DOI 10.1006/JMBI.1999.3023 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3fay IQGAP1 crystal structure of the gap-related domain of iqgap1 2.2Å AUTH V.B.KURELLA,J.M.RICHARD,C.L.PARKE,L.F.LECOUR,AUTH 2 H.D.BELLAMY,D.K.WORTHYLAKETITL CRYSTAL STRUCTURE OF THE GTPASE-ACTIVATINGTITL 2 PROTEIN-RELATED DOMAIN FROM IQGAP1.REF J.BIOL.CHEM. V. 284 14857 2009REFN ISSN 0021-9258PMID 19321438DOI 10.1074/JBC.M808974200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4go6 HCFC1 crystal structure of hcf-1 self-association sequence 1 2.7Å AUTH J.PARK,F.LAMMERS,W.HERR,J.SONGTITL HCF-1 SELF-ASSOCIATION VIA AN INTERDIGITATED FN3 STRUCTURETITL 2 FACILITATES TRANSCRIPTIONAL REGULATORY COMPLEX FORMATIONREF PROC.NATL.ACAD.SCI.USA V. 109 17430 2012REFN ISSN 0027-8424PMID 23045687DOI 10.1073/PNAS.1208378109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3eh2 SEC24C crystal structure of the human copii-coat protein sec24c 2.35Å AUTH J.D.MANCIAS,J.GOLDBERGTITL STRUCTURAL BASIS OF CARGO MEMBRANE PROTEINTITL 2 DISCRIMINATION BY THE HUMAN COPII COAT MACHINERY.REF EMBO J. V. 27 2918 2008REFN ISSN 0261-4189PMID 18843296DOI 10.1038/EMBOJ.2008.208 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ja3 CLCN5 cytoplasmic domain of the human chloride transporter clc-5 in complex with adp 3.05Å AUTH S.MEYER,S.SAVARESI,I.C.FORSTER,R.DUTZLERTITL NUCLEOTIDE RECOGNITION BY THE CYTOPLASMIC DOMAINTITL 2 OF THE HUMAN CHLORIDE TRANSPORTER CLC-5REF NAT.STRUCT.MOL.BIOL. V. 14 60 2006REFN ISSN 1545-9993PMID 17195847DOI 10.1038/NSMB1188 Variant Set Distributions Mapped Variants
General Structure Information 2ys1 DNM2 solution structure of the ph domain of dynamin-2 from human -1.0Å AUTH H.LI,M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF DYNAMIN-2TITL 2 FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1ds6 ARHGDIB crystal structure of a rac-rhogdi complex 2.35Å AUTH K.SCHEFFZEK,I.STEPHAN,O.N.JENSEN,D.ILLENBERGER,AUTH 2 P.GIERSCHIKTITL THE RAC-RHOGDI COMPLEX AND THE STRUCTURAL BASISTITL 2 FOR THE REGULATION OF RHO PROTEINS BY RHOGDI.REF NAT.STRUCT.BIOL. V. 7 122 2000REFN ISSN 1072-8368PMID 10655614DOI 10.1038/72392 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]