Assessment of Structural Intolerance and Durability
General Structure Information 2csf SATB2 solution structure of the second cut domain of human satb2 -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND CUT DOMAIN OFTITL 2 HUMAN SATB2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mop IRAK4 the ternary death domain complex of myd88, irak4, and irak2 3.4Å AUTH S.C.LIN,Y.C.LO,H.WUTITL HELICAL ASSEMBLY IN THE MYD88-IRAK4-IRAK2 COMPLEX INTITL 2 TLR/IL-1R SIGNALLING.REF NATURE V. 465 885 2010REFN ISSN 0028-0836PMID 20485341DOI 10.1038/NATURE09121 Variant Set Distributions Mapped Variants
General Structure Information 3nwn KIF9 crystal structure of the human kif9 motor domain in complex with adp 2.0Å AUTH H.ZHU,W.TEMPEL,H.HE,Y.SHEN,J.WANG,G.BROTHERS,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE HUMAN KIF9 MOTOR DOMAIN IN COMPLEXTITL 2 WITH ADPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2err RBFOX1 nmr structure of the rna binding domain of human fox-1 in complex with ugcaugu -1.0Å AUTH S.D.AUWETER,R.FASAN,L.REYMOND,J.G.UNDERWOOD,AUTH 2 D.L.BLACK,S.PITSCH,F.H.ALLAINTITL MOLECULAR BASIS OF RNA RECOGNITION BY THE HUMANTITL 2 ALTERNATIVE SPLICING FACTOR FOX-1.REF EMBO J. V. 25 163 2006REFN ISSN 0261-4189PMID 16362037DOI 10.1038/SJ.EMBOJ.7600918 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3nhb ABCB6 nucleotide binding domain of human abcb6 (adp bound structure) 2.15Å AUTH M.HAFFKE,A.MENZEL,Y.CARIUS,D.JAHN,D.W.HEINZTITL STRUCTURES OF THE NUCLEOTIDE-BINDING DOMAIN OF THE HUMANTITL 2 ABCB6 TRANSPORTER AND ITS COMPLEXES WITH NUCLEOTIDES.REF ACTA CRYSTALLOGR.,SECT.D V. 66 979 2010REFN ISSN 0907-4449PMID 20823549DOI 10.1107/S0907444910028593 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 2kt0 NANOG solution structure of human stem cell transcription factor nanog homeodomain fragment -1.0Å AUTH S.C.SAHU,J.L.MARKLEYTITL SOLUTION STRUCTURE OF HUMAN STEM CELL TRANSCRIPTION FACTORTITL 2 NANOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3au5 MYO10 structure of the human myosin-x myth4-ferm cassette 2.55Å AUTH Y.HIRANO,T.HATANO,A.TAKAHASHI,M.TORIYAMA,N.INAGAKI,AUTH 2 T.HAKOSHIMATITL STRUCTURAL BASIS OF CARGO RECOGNITION BY THE MYOSIN-XTITL 2 MYTH4-FERM DOMAINREF EMBO J. V. 30 2734 2011REFN ISSN 0261-4189PMID 21642953DOI 10.1038/EMBOJ.2011.177 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jq6 EHD1 structure of eh-domain of ehd1 -1.0Å AUTH F.KIEKEN,M.JOVIC,N.NASLAVSKY,S.CAPLAN,P.L.SORGENTITL EH DOMAIN OF EHD1REF J.BIOMOL.NMR V. 39 323 2007REFN ISSN 0925-2738PMID 17899392DOI 10.1007/S10858-007-9196-0 Variant Set Distributions Mapped Variants
General Structure Information 4fo0 ACTR8 human actin-related protein arp8 in its atp-bound state 2.6Å AUTH C.B.GERHOLD,D.D.WINKLER,K.LAKOMEK,F.U.SEIFERT,S.FENN,AUTH 2 B.KESSLER,G.WITTE,K.LUGER,K.P.HOPFNERTITL STRUCTURE OF ACTIN-RELATED PROTEIN 8 AND ITS CONTRIBUTION TOTITL 2 NUCLEOSOME BINDING.REF NUCLEIC ACIDS RES. V. 40 11036 2012REFN ISSN 0305-1048PMID 22977180DOI 10.1093/NAR/GKS842 Variant Set Distributions Mapped Variants
General Structure Information 2ds4 TRIM45 solution structure of the filamin domain from human tripartite motif protein 45 -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FILAMIN DOMAIN FROMTITL 2 HUMAN TRIPARTITE MOTIF PROTEIN 45REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants