Assessment of Structural Intolerance and Durability
General Structure Information 1lg4 PRND nmr structure of the human doppel protein fragment 24-152 -1.0Å AUTH T.LUHRS,R.RIEK,P.GUNTERT,K.WUTHRICHTITL NMR STRUCTURE OF THE HUMAN DOPPEL PROTEINREF J.MOL.BIOL. V. 326 1549 2003REFN ISSN 0022-2836PMID 12595265DOI 10.1016/S0022-2836(02)01471-7 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2q13 APPL1 crystal structure of bar-ph domain of appl1 2.05Å AUTH G.ZHU,J.CHEN,J.LIU,J.S.BRUNZELLE,B.HUANG,N.WAKEHAM,AUTH 2 S.TERZYAN,X.LI,Z.RAO,G.LI,X.C.ZHANGTITL STRUCTURE OF THE APPL1 BAR-PH DOMAIN AND CHARACTERIZATION OFTITL 2 ITS INTERACTION WITH RAB5.REF EMBO J. V. 26 3484 2007REFN ISSN 0261-4189PMID 17581628DOI 10.1038/SJ.EMBOJ.7601771 Variant Set Distributions Mapped Variants
General Structure Information 2k3w VPS4A nmr structure of vps4a-mit-chmp6 -1.0Å AUTH C.KIEFFER,J.J.SKALICKY,E.MORITA,I.DE DOMENICO,AUTH 2 D.M.WARD,J.KAPLAN,W.I.SUNDQUISTTITL TWO DISTINCT MODES OF ESCRT-III RECOGNITION ARETITL 2 REQUIRED FOR VPS4 FUNCTIONS IN LYSOSOMAL PROTEINTITL 3 TARGETING AND HIV-1 BUDDINGREF DEV.CELL V. 15 62 2008REFN ISSN 1534-5807PMID 18606141DOI 10.1016/J.DEVCEL.2008.05.014 Variant Set Distributions Mapped Variants
General Structure Information 2edp SHROOM4 solution structure of the pdz domain from human shroom family member 4 -1.0Å AUTH H.ENDO,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN FROM HUMANTITL 2 SHROOM FAMILY MEMBER 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1uhp PDZRN3 solution structure of rsgi ruh-005, a pdz domain in human cdna, kiaa1095 -1.0Å AUTH T.HAMADA,Y.MUTO,H.HIROTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-005, A PDZ DOMAINTITL 2 IN HUMAN CDNA, KIAA1095REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2i7t CPSF3 structure of human cpsf-73 2.1Å AUTH C.R.MANDEL,S.KANEKO,H.ZHANG,D.GEBAUER,V.VETHANTHAM,AUTH 2 J.L.MANLEY,L.TONGTITL POLYADENYLATION FACTOR CPSF-73 IS THE PRE-MRNATITL 2 3-END-PROCESSING ENDONUCLEASE.REF NATURE V. 444 953 2006REFN ISSN 0028-0836PMID 17128255DOI 10.1038/NATURE05363 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2r13 CISD1 crystal structure of human mitoneet reveals a novel [2fe- 2s] cluster coordination 1.8Å AUTH X.HOU,R.LIU,S.ROSS,E.J.SMART,H.ZHU,W.GONGTITL CRYSTALLOGRAPHIC STUDIES OF HUMAN MITONEETREF J.BIOL.CHEM. V. 282 33242 2007REFN ISSN 0021-9258PMID 17905743DOI 10.1074/JBC.C700172200 Variant Set Distributions Mapped Variants
General Structure Information 1wj3 CNTN3 solution structure of the fourth fn3 domain of kiaa1496 protein -1.0Å AUTH K.INOUE,T.NAGASHIMA,N.TOCHIO,T.KIGAWA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FOURTH FN3 DOMAIN OFTITL 2 KIAA1496 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2cqe ZC3H4 solution structure of the zinc-finger domain in kiaa1064 protein -1.0Å AUTH T.SOMEYA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZINC-FINGER DOMAIN INTITL 2 KIAA1064 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mdj ERAP1 er aminopeptidase, erap1, bound to the zinc aminopeptidase inhibitor, bestatin 2.95Å AUTH T.T.NGUYEN,S.C.CHANG,I.EVNOUCHIDOU,I.A.YORK,C.ZIKOS,AUTH 2 K.L.ROCK,A.L.GOLDBERG,E.STRATIKOS,L.J.STERNTITL STRUCTURAL BASIS FOR ANTIGENIC PEPTIDE PRECURSOR PROCESSINGTITL 2 BY THE ENDOPLASMIC RETICULUM AMINOPEPTIDASE ERAP1.REF NAT.STRUCT.MOL.BIOL. V. 18 604 2011REFN ISSN 1545-9993PMID 21478864DOI 10.1038/NSMB.2021 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants