Assessment of Structural Intolerance and Durability
General Structure Information 2kna XIAP solution structure of uba domain of xiap -1.0Å AUTH S.K.HUI,M.K.TSE,Y.YANG,B.C.WONG,K.H.SZETITL BACKBONE AND SIDE-CHAIN 1H, 13C AND 15N ASSIGNMENTS OF THETITL 2 UBIQUITIN-ASSOCIATED DOMAIN OF HUMAN X-LINKED INHIBITOR OFTITL 3 APOPTOSIS PROTEINREF BIOMOL.NMR ASSIGN. V. 4 13 2010REFN ISSN 1874-2718PMID 19916060DOI 10.1007/S12104-009-9197-X Variant Set Distributions Mapped Variants
General Structure Information 4dgj TMPRSS15 structure of a human enteropeptidase light chain variant 1.9Å AUTH P.SIMEONOV,M.ZAHN,N.STRATER,T.ZUCHNERTITL CRYSTAL STRUCTURE OF A SUPERCHARGED VARIANT OF THE HUMANTITL 2 ENTEROPEPTIDASE LIGHT CHAIN.REF PROTEINS V. 80 1907 2012REFN ISSN 0887-3585PMID 22488687DOI 10.1002/PROT.24084 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2leo SPINK7 solution structure of esophageal cancer-related gene 2 -1.0Å AUTH Y.FENG,Y.GENG,T.ZHOU,J.WANGTITL NMR STRUCTURE NOTE: HUMAN ESOPHAGEAL CANCER-RELATED GENE 2REF J.BIOMOL.NMR V. 53 65 2012REFN ISSN 0925-2738PMID 22528291DOI 10.1007/S10858-012-9622-9 Variant Set Distributions Mapped Variants
General Structure Information 1w50 BACE1 apo structure of bace (beta secretase) 1.75Å AUTH S.PATEL,L.VUILLARD,A.CLEASBY,C.W.MURRAY,J.YONTITL APO AND INHIBITOR COMPLEX STRUCTURES OF BACETITL 2 (BETA-SECRETASE)REF J.MOL.BIOL. V. 343 407 2004REFN ISSN 0022-2836PMID 15451669DOI 10.1016/J.JMB.2004.08.018 Variant Set Distributions Mapped Variants
General Structure Information 3dpr VLDLR human rhinovirus 2 bound to a concatamer of the vldl receptor module v3 3.5Å AUTH J.QUEROL-AUDI,T.KONECSNI,J.POUS,O.CARUGO,I.FITA,N.VERDAGUER,AUTH 2 D.BLAASTITL MINOR GROUP HUMAN RHINOVIRUS-RECEPTOR INTERACTIONS: GEOMETRYTITL 2 OF MULTIMODULAR ATTACHMENT AND BASIS OF RECOGNITIONREF FEBS LETT. V. 583 235 2009REFN ISSN 0014-5793PMID 19073182DOI 10.1016/J.FEBSLET.2008.12.014 Variant Set Distributions Mapped Variants
General Structure Information 3bxm FOLH1 structure of an inactive mutant of human glutamate carboxypeptidase ii [gcpii(e424a)] in complex with n-acetyl-asp-glu (naag) 1.71Å AUTH V.KLUSAK,C.BARINKA,A.PLECHANOVOVA,P.MLCOCHOVA,J.KONVALINKA,AUTH 2 L.RULISEK,J.LUBKOWSKITITL REACTION MECHANISM OF GLUTAMATE CARBOXYPEPTIDASE II REVEALEDTITL 2 BY MUTAGENESIS, X-RAY CRYSTALLOGRAPHY, AND COMPUTATIONALTITL 3 METHODS.REF BIOCHEMISTRY V. 48 4126 2009REFN ISSN 0006-2960PMID 19301871DOI 10.1021/BI900220S Variant Set Distributions Ripley’s […]
General Structure Information 1z68 FAP crystal structure of human fibroblast activation protein alpha 2.6Å AUTH K.AERTGEERTS,I.LEVIN,L.SHI,G.P.SNELL,A.JENNINGS,G.S.PRASAD,AUTH 2 Y.ZHANG,M.L.KRAUS,S.SALAKIAN,V.SRIDHAR,R.WIJNANDS,AUTH 3 M.G.TENNANTTITL STRUCTURAL AND KINETIC ANALYSIS OF THE SUBSTRATE SPECIFICITYTITL 2 OF HUMAN FIBROBLAST ACTIVATION PROTEIN ALPHA.REF J.BIOL.CHEM. V. 280 19441 2005REFN ISSN 0021-9258PMID 15809306DOI 10.1074/JBC.C500092200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 2kna XIAP solution structure of uba domain of xiap -1.0Å AUTH S.K.HUI,M.K.TSE,Y.YANG,B.C.WONG,K.H.SZETITL BACKBONE AND SIDE-CHAIN 1H, 13C AND 15N ASSIGNMENTS OF THETITL 2 UBIQUITIN-ASSOCIATED DOMAIN OF HUMAN X-LINKED INHIBITOR OFTITL 3 APOPTOSIS PROTEINREF BIOMOL.NMR ASSIGN. V. 4 13 2010REFN ISSN 1874-2718PMID 19916060DOI 10.1007/S12104-009-9197-X Variant Set Distributions Mapped Variants
General Structure Information 4dgj TMPRSS15 structure of a human enteropeptidase light chain variant 1.9Å AUTH P.SIMEONOV,M.ZAHN,N.STRATER,T.ZUCHNERTITL CRYSTAL STRUCTURE OF A SUPERCHARGED VARIANT OF THE HUMANTITL 2 ENTEROPEPTIDASE LIGHT CHAIN.REF PROTEINS V. 80 1907 2012REFN ISSN 0887-3585PMID 22488687DOI 10.1002/PROT.24084 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2leo SPINK7 solution structure of esophageal cancer-related gene 2 -1.0Å AUTH Y.FENG,Y.GENG,T.ZHOU,J.WANGTITL NMR STRUCTURE NOTE: HUMAN ESOPHAGEAL CANCER-RELATED GENE 2REF J.BIOMOL.NMR V. 53 65 2012REFN ISSN 0925-2738PMID 22528291DOI 10.1007/S10858-012-9622-9 Variant Set Distributions Mapped Variants