Assessment of Structural Intolerance and Durability
General Structure Information 3edi TLL1 crystal structure of tolloid-like protease 1 (tll-1) protease domain 1.4Å AUTH A.MAC SWEENEY,S.G.PARRADO,D.VINZENZ,A.BERNARDI,AUTH 2 A.HEIN,U.BODENDORF,P.ERBEL,C.LOGEL,B.GERHARTZTITL STRUCTURAL BASIS FOR THE SUBSTRATE SPECIFICITY OFTITL 2 BONE MORPHOGENETIC PROTEIN 1/TOLLOID-LIKETITL 3 METALLOPROTEASESREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3v6c USP2 crystal structure of usp2 in complex with mutated ubiquitin 1.7Å AUTH M.NECULAI,A.ERNST,S.SIDHU,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 C.BOUNTRA,J.WEIGELT,S.DHE-PAGANONTITL CRYSTAL STRUCTURE OF USP2 IN COMPLEX WITH MUTATED UBIQUITINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3kfq CTSV unreduced cathepsin v in complex with stefin a 1.99Å AUTH M.RENKO,D.TURKTITL UNREDUCED CATHEPSIN V IN COMPLEX WITH STEFIN AREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ee6 TPP1 crystal structure analysis of tripeptidyl peptidase -i 2.35Å AUTH A.PAL,R.KRAETZNER,T.GRUENE,M.GRAPP,K.SCHREIBER,M.GRONBORG,AUTH 2 H.URLAUB,S.BECKER,A.R.ASIF,J.GARTNER,G.M.SHELDRICK,AUTH 3 R.STEINFELDTITL STRUCTURE OF TRIPEPTIDYL-PEPTIDASE I PROVIDES INSIGHT INTOTITL 2 THE MOLECULAR BASIS OF LATE INFANTILE NEURONAL CEROIDTITL 3 LIPOFUSCINOSISREF J.BIOL.CHEM. V. 284 3976 2009REFN ISSN 0021-9258PMID 19038966DOI 10.1074/JBC.M806947200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3h11 CFLAR zymogen caspase-8:c-flipl protease domain complex 1.9Å AUTH J.W.YU,P.D.JEFFREY,Y.SHITITL MECHANISM OF PROCASPASE-8 ACTIVATION BY C-FLIPL.REF PROC.NATL.ACAD.SCI.USA V. 106 8169 2009REFN ISSN 0027-8424PMID 19416807DOI 10.1073/PNAS.0812453106 Variant Set Distributions Mapped Variants
General Structure Information 2wfq DHH crystal structure of the n-terminal signalling domain of human dhh without calcium 1.85Å AUTH B.BISHOP,A.R.ARICESCU,K.HARLOS,C.A.OCALLAGHAN,E.Y.JONES,AUTH 2 C.SIEBOLDTITL STRUCTURAL INSIGHTS INTO HEDGEHOG LIGAND SEQUESTRATION BYTITL 2 THE HUMAN HEDGEHOG-INTERACTING PROTEIN HIPREF NAT.STRUCT.MOL.BIOL. V. 16 698 2009REFN ISSN 1545-9993PMID 19561611DOI 10.1038/NSMB.1607 Variant Set Distributions Mapped Variants