Assessment of Structural Intolerance and Durability
General Structure Information 2qfe CAPN7 distal c2-like domain of human calpain-7 1.45Å AUTH J.R.WALKER,D.CUERRIER,R.RAVULAPALLI,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 S.DHE-PAGANONTITL STRUCTURE OF THE C2 DOMAIN OF HUMAN CALPAIN-7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ihr UCHL5 crystal structure of uch37 2.95Å AUTH S.E.BURGIE,C.A.BINGMAN,A.B.SONI,G.N.PHILLIPSTITL STRUCTURAL CHARACTERIZATION OF HUMAN UCH37.REF PROTEINS 2011REFN ESSN 1097-0134PMID 21953935DOI 10.1002/PROT.23147 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ff3 NAALAD2 the high resolution structure of human glutamate carboxypeptidase iii (gcpiii/naaladase ii) in complex with l-glutamate 1.37Å AUTH K.HLOUCHOVA,C.BARINKA,J.KONVALINKA,J.LUBKOWSKITITL STRUCTURAL INSIGHT INTO THE EVOLUTIONARY AND PHARMACOLOGICTITL 2 HOMOLOGY OF GLUTAMATE CARBOXYPEPTIDASES II AND IIIREF FEBS J. V. 276 4448 2009REFN ISSN 1742-464XPMID 19678840DOI 10.1111/J.1742-4658.2009.07152.X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3t9l USP15 structure of n-terminal dusp-ubl domains of human usp15 1.5Å AUTH S.HARPER,T.M.BESONG,J.EMSLEY,D.J.SCOTT,I.DREVENYTITL STRUCTURE OF THE USP15 N-TERMINAL DOMAINS: A BETA-HAIRPINTITL 2 MEDIATES CLOSE ASSOCIATION BETWEEN THE DUSP AND UBL DOMAINSREF BIOCHEMISTRY V. 50 7995 2011REFN ISSN 0006-2960PMID 21848306DOI 10.1021/BI200726E Variant Set Distributions Mapped Variants
General Structure Information 2qz4 SPG7 human paraplegin, aaa domain in complex with adp 2.22Å AUTH T.KARLBERG,S.VAN DEN BERG,M.HAMMARSTROM,J.SAGEMARK,AUTH 2 I.JOHANSSON,L.HOLMBERG-SCHIAVONE,H.SCHULERTITL CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF THE HUMAN AAA+TITL 2 PROTEIN PARAPLEGIN/SPG7.REF PLOS ONE V. 4 E6975 2009REFN ESSN 1932-6203PMID 19841671DOI 10.1371/JOURNAL.PONE.0006975 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3k0w MALT1 crystal structure of the tandem ig-like c2-type 2 domains of the human mucosa-associated lymphoid tissue lymphoma translocation protein 1 2.8Å AUTH J.R.WALKER,L.QIU,C.BUTLER-COLE,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 S.DHE-PAGANONTITL STRUCTURE OF THE TANDEM IG-LIKE C2-TYPE 2 DOMAINSTITL 2 OF THE HUMAN MUCOSA-ASSOCIATED LYMPHOID TISSUETITL 3 LYMPHOMA TRANSLOCATION PROTEIN 1.REF TO BE PUBLISHEDREFN Variant […]
General Structure Information 2oq5 TMPRSS11E crystal structure of desc1, a new member of the type ii transmembrane serine proteinases family 1.61Å AUTH O.J.P.KYRIELEIS,R.HUBER,E.ONG,R.OEHLER,M.HUNTER,AUTH 2 E.L.MADISON,U.JACOBTITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OFTITL 2 DESC1, A NEW MEMBER OF THE TYPE II TRANSMEMBRANETITL 3 SERINE PROTEINASE FAMILY.REF FEBS J. V. 274 2148 2007REFN ISSN 1742-464XPMID 17388811DOI […]
General Structure Information 3jyh DPP7 human dipeptidyl peptidase dpp7 2.19Å AUTH E.DOBROVETSKY,A.DONG,A.SEITOVA,L.CROMBETT,S.PAGANON,AUTH 2 D.COSSAR,A.M.EDWARDS,C.H.ARROWSMITH,C.BOUNTRA,J.WEIGELT,AUTH 3 A.HASSEL,L.SHEWCHUK,A.BOCHKAREVTITL HUMAN DIPEPTIDYL PEPTIDASE DPP7REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3jtc PROCR importance of mg2+ in the ca2+-dependent folding of the gamma- carboxyglutamic acid domains of vitamin k-dependent clotting and anticlotting proteins 1.6Å AUTH K.VADIVEL,S.AGAH,A.S.MESSER,D.CASCIO,M.S.BAJAJ,AUTH 2 S.KRISHNASWAMY,C.T.ESMON,K.PADMANABHAN,S.P.BAJAJTITL STRUCTURAL AND FUNCTIONAL STUDIES OF GAMMA-CARBOXYGLUTAMICTITL 2 ACID DOMAINS OF FACTOR VIIA AND ACTIVATED PROTEIN C: ROLE OFTITL 3 MAGNESIUM AT PHYSIOLOGICAL CALCIUM.REF J.MOL.BIOL. V. […]
General Structure Information 2xph SENP1 crystal structure of human senp1 with the bound cobalt 2.4Å AUTH V.RIMSA,T.EADSFORTH,R.T.HAY,W.N.HUNTERTITL THE ROLE OF CO2+ IN THE CRYSTALLIZATION OF HUMAN SENP1 ANDTITL 2 COMMENTS ON THE LIMITATIONS OF AUTOMATED REFINEMENTTITL 3 PROTOCOLSREF ACTA CRYSTALLOGR.,SECT.F V. 67 442 2011REFN ISSN 1744-3091PMID 21505236DOI 10.1107/S1744309111005835 Variant Set Distributions Mapped Variants