General Structure Information
| PDB ID | 2oq5 |
| HGNC Gene Label(s) | TMPRSS11E |
| Structure Name | crystal structure of desc1, a new member of the type ii transmembrane serine proteinases family |
| Resolution | 1.61Å |
| Reference | AUTH O.J.P.KYRIELEIS,R.HUBER,E.ONG,R.OEHLER,M.HUNTER,AUTH 2 E.L.MADISON,U.JACOBTITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OFTITL 2 DESC1, A NEW MEMBER OF THE TYPE II TRANSMEMBRANETITL 3 SERINE PROTEINASE FAMILY.REF FEBS J. V. 274 2148 2007REFN ISSN 1742-464XPMID 17388811DOI 10.1111/J.1742-4658.2007.05756.X |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 221 |
| Number Of SNVs | 64 |
| Number Of Permutations | 19617 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.141 |
| p-value | 0.043 |
COSMIC
| Number Of Residues | 221 |
| Number Of SNVs | 4 |
| Number Of Permutations | 265 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.167 |
| p-value | 0.464 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 64 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.128 |
| p-value | 0.609 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
