Assessment of Structural Intolerance and Durability
General Structure Information 3m66 MTERFD1 crystal structure of human mitochondrial transcription termination factor 3 1.6Å AUTH H.SPAHR,T.SAMUELSSON,B.M.HALLBERG,C.M.GUSTAFSSONTITL STRUCTURE OF MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTORTITL 2 3 REVEALS A NOVEL NUCLEIC ACID-BINDING DOMAIN.REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 397 386 2010REFN ISSN 0006-291XPMID 20430012DOI 10.1016/J.BBRC.2010.04.130 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2r02 PDCD6IP crystal structure of alix/aip1 in complex with the hiv-1 ypltsl late domain 2.6Å AUTH Q.ZHAI,R.D.FISHER,H.Y.CHUNG,D.G.MYSZKA,AUTH 2 W.I.SUNDQUIST,C.P.HILLTITL STRUCTURAL AND FUNCTIONAL STUDIES OF ALIXTITL 2 INTERACTIONS WITH YPX(N)L LATE DOMAINS OF HIV-1TITL 3 AND EIAV.REF NAT.STRUCT.MOL.BIOL. V. 15 43 2008REFN ISSN 1545-9993PMID 18066081DOI 10.1038/NSMB1319 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 4f9z ERP27 crystal structure of human erp27 2.2Å AUTH F.X.KOBER,W.KOELMEL,J.KUPER,J.DRECHSLER,C.MAIS,H.M.HERMANNS,AUTH 2 H.SCHINDELINTITL THE CRYSTAL STRUCTURE OF THE PROTEIN-DISULFIDE ISOMERASETITL 2 FAMILY MEMBER ERP27 PROVIDES INSIGHTS INTO ITS SUBSTRATETITL 3 BINDING CAPABILITIES.REF J.BIOL.CHEM. V. 288 2029 2013REFN ISSN 0021-9258PMID 23192347DOI 10.1074/JBC.M112.410522 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2vn8 RTN4IP1 crystal structure of human reticulon 4 interacting protein 1 in complex with nadph 2.1Å AUTH A.C.W.PIKE,K.GUO,J.ELKINS,E.UGOCHUKWU,A.K.ROOS,AUTH 2 P.FILIPPAKOPOULOS,F.VON DELFT,A.EDWARDS,C.H.ARROWSMITH,AUTH 3 J.WEIGELT,C.BOUNTRA,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN RETICULON 4 INTERACTING PROTEINTITL 2 1 IN COMPLEX WITH NADPHREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 4l1u RTF1 crystal structure of human rtf1 plus3 domain in complex with spt5 ctr phosphopeptide 2.42Å AUTH A.D.WIER,M.K.MAYEKAR,A.HEROUX,K.M.ARNDT,A.P.VANDEMARKTITL STRUCTURAL BASIS FOR SPT5-MEDIATED RECRUITMENT OF THE PAF1TITL 2 COMPLEX TO CHROMATIN.REF PROC.NATL.ACAD.SCI.USA V. 110 17290 2013REFN ISSN 0027-8424PMID 24101474DOI 10.1073/PNAS.1314754110 Variant Set Distributions Mapped Variants
General Structure Information 3f7g BIRC7 structure of the bir domain from ml-iap bound to a peptidomimetic 2.3Å AUTH F.COHEN,B.ALICKE,L.O.ELLIOTT,J.A.FLYGARE,T.GONCHAROV,AUTH 2 S.F.KETELTAS,M.C.FRANKLIN,S.FRANKOVITZ,J.P.STEPHAN,V.TSUI,AUTH 3 D.VUCIC,H.WONG,W.J.FAIRBROTHERTITL ORALLY BIOAVAILABLE ANTAGONISTS OF INHIBITOR OF APOPTOSISTITL 2 PROTEINS BASED ON AN AZABICYCLOOCTANE SCAFFOLDREF J.MED.CHEM. V. 52 1723 2009REFN ISSN 0022-2623PMID 19228017DOI 10.1021/JM801450C Variant Set Distributions Mapped Variants
General Structure Information 1h6e AP2M1 mu2 adaptin subunit (ap50) of ap2 adaptor (second domain), complexed with ctla-4 internalization peptide ttgvyvkmppt 3.6Å AUTH E.R.FOLLOWS,J.C.MCPHEAT,C.MINSHULL,N.C.MOORE,AUTH 2 R.A.PAUPTIT,S.ROWSELL,C.L.STACEY,J.J.STANWAY,AUTH 3 I.W.TAYLOR,W.M.ABBOTTTITL STUDY OF THE INTERACTION OF THE MEDIUM CHAIN MU2TITL 2 SUBUNIT OF THE CLATHRIN-ASSOCIATED ADAPTER PROTEINTITL 3 COMPLEX 2 WITH CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4TITL 4 AND CD28REF BIOCHEM.J. […]
General Structure Information 3ueo TOPBP1 crystal structure of topbp1 brct4/5 domains in complex with a phospho- peptide 2.6Å AUTH C.C.LEUNG,L.SUN,Z.GONG,M.BURKAT,R.EDWARDS,M.ASSMUS,J.CHEN,AUTH 2 J.N.GLOVERTITL STRUCTURAL INSIGHTS INTO RECOGNITION OF MDC1 BY TOPBP1 INTITL 2 DNA REPLICATION CHECKPOINT CONTROL.REF STRUCTURE V. 21 1450 2013REFN ISSN 0969-2126PMID 23891287DOI 10.1016/J.STR.2013.06.015 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2edi UBE2F solution structure of the uq_con domain from human nedd8- conjugating enzyme nce2 -1.0Å AUTH H.ENDO,K.IZUMI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE UQ_CON DOMAIN FROM HUMANTITL 2 NEDD8-CONJUGATING ENZYME NCE2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2m38 ANKS1B ptb domain of aida1 -1.0Å AUTH L.DONALDSONTITL TO BE PUBLISHEDREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants