Assessment of Structural Intolerance and Durability
General Structure Information 3abd MAD2L2 structure of human rev7 in complex with a human rev3 fragment in a monoclinic crystal 1.9Å AUTH K.HARA,H.HASHIMOTO,Y.MURAKUMO,S.KOBAYASHI,T.KOGAME,S.UNZAI,AUTH 2 S.AKASHI,S.TAKEDA,T.SHIMIZU,M.SATOTITL CRYSTAL STRUCTURE OF HUMAN REV7 IN COMPLEX WITH A HUMAN REV3TITL 2 FRAGMENT AND STRUCTURAL IMPLICATION OF THE INTERACTIONTITL 3 BETWEEN DNA POLYMERASE {ZETA} AND REV1REF J.BIOL.CHEM. V. 285 12299 […]
General Structure Information 4gmj CNOT7 structure of human not1 mif4g domain co-crystallized with caf1 2.7Å AUTH A.P.PETIT,L.WOHLBOLD,P.BAWANKAR,E.HUNTZINGER,S.SCHMIDT,AUTH 2 E.IZAURRALDE,O.WEICHENRIEDERTITL THE STRUCTURAL BASIS FOR THE INTERACTION BETWEEN THE CAF1TITL 2 NUCLEASE AND THE NOT1 SCAFFOLD OF THE HUMAN CCR4-NOTTITL 3 DEADENYLASE COMPLEXREF NUCLEIC ACIDS RES. V. 40 11058 2012REFN ISSN 0305-1048PMID 22977175DOI 10.1093/NAR/GKS883 Variant Set Distributions […]
General Structure Information 4avm BIN2 crystal structure of the n-bar domain of human bridging integrator 2. 1.91Å AUTH C.K.ALLERSTON,T.KROJER,C.D.O.COOPER,M.VOLLMAR,AUTH 2 C.H.ARROWSMITH,A.EDWARDS,C.BOUNTRA,F.VON DELFT,O.GILEADITITL CRYSTAL STRUCTURE OF THE N-BAR DOMAIN OF HUMAN BRIDGINGTITL 2 INTEGRATOR 2.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2lkt RARRES3 solution structure of n-terminal domain of human tig3 in 2 m urea -1.0Å AUTH L.WANG,W.YU,X.REN,J.LIN,C.JIN,B.XIATITL (1)H, (13)C, AND (15)N RESONANCE ASSIGNMENTS OF THETITL 2 N-TERMINAL DOMAIN OF HUMAN TIG3REF BIOMOL.NMR ASSIGN. V. 6 201 2012REFN ISSN 1874-2718PMID 22290676DOI 10.1007/S12104-012-9357-2 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 4hxi KLHL3 crystal structure of klhl3/cul3 complex 3.51Å AUTH A.X.JI,G.G.PRIVETITL STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF KLHL3/CUL3TITL 2 COMPLEX AND IMPLICATIONS OF FHHT MUTATIONS IN CUL3 BINDINGREF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ox6 CABP1 crystal structure of the calcium sensor calcium-binding protein 1 (cabp1) 2.4Å AUTH F.FINDEISEN,D.L.MINORTITL STRUCTURAL BASIS FOR THE DIFFERENTIAL EFFECTS OF CABP1 ANDTITL 2 CALMODULIN ON CA(V)1.2 CALCIUM-DEPENDENT INACTIVATION.REF STRUCTURE V. 18 1617 2010REFN ISSN 0969-2126PMID 21134641DOI 10.1016/J.STR.2010.09.012 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2oq5 TMPRSS11E crystal structure of desc1, a new member of the type ii transmembrane serine proteinases family 1.61Å AUTH O.J.P.KYRIELEIS,R.HUBER,E.ONG,R.OEHLER,M.HUNTER,AUTH 2 E.L.MADISON,U.JACOBTITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OFTITL 2 DESC1, A NEW MEMBER OF THE TYPE II TRANSMEMBRANETITL 3 SERINE PROTEINASE FAMILY.REF FEBS J. V. 274 2148 2007REFN ISSN 1742-464XPMID 17388811DOI […]
General Structure Information 2w0u HAO1 crystal structure of human glycolate oxidase in complex with the inhibitor 5-[(4-chlorophenyl)sulfanyl]- 1,2,3-thiadiazole-4-carboxylate. 2.84Å AUTH J.M.BOURHIS,C.VIGNAUD,N.PIETRANCOSTA,F.GUERITTE,AUTH 2 D.GUENARD,F.LEDERER,Y.LINDQVISTTITL STRUCTURE OF HUMAN GLYCOLATE OXIDASE IN COMPLEXTITL 2 WITH THE INHIBITOR 4-CARBOXY-5-[(4-TITL 3 CHLOROPHENYL)SULFANYL]-1,2,3-THIADIAZOLE.REF ACTA CRYSTALLOGR.,SECT.F V. 65 1246 2009REFN ISSN 1744-3091PMID 20054120DOI 10.1107/S1744309109041670 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2iwi PIM2 crystal structure of the human pim2 in complex with a ruthenium organometallic ligand ru1 2.8Å AUTH A.N.BULLOCK,S.RUSSO,A.AMOS,N.PAGANO,H.BREGMAN,AUTH 2 J.E.DEBRECZENI,W.H.LEE,F.VON DELFT,E.MEGGERS,AUTH 3 S.KNAPPTITL CRYSTAL STRUCTURE OF THE PIM2 KINASE IN COMPLEXTITL 2 WITH AN ORGANORUTHENIUM INHIBITOR.REF PLOS ONE V. 4 E7112 2009REFN ISSN 1932-6203PMID 19841674DOI 10.1371/JOURNAL.PONE.0007112 Variant Set Distributions Ripley’s K […]
General Structure Information 3gqc REV1 structure of human rev1-dna-dntp ternary complex 2.5Å AUTH M.K.SWAN,R.E.JOHNSON,L.PRAKASH,S.PRAKASH,A.K.AGGARWALTITL STRUCTURE OF THE HUMAN REV1-DNA-DNTP TERNARY COMPLEX.REF J.MOL.BIOL. V. 390 699 2009REFN ISSN 0022-2836PMID 19464298DOI 10.1016/J.JMB.2009.05.026 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants