Assessment of Structural Intolerance and Durability
General Structure Information 4fzs SNX1 structure of human snx1 bar domain 2.8Å AUTH J.R.T.VAN WEERING,R.B.SESSIONS,C.J.TRAER,D.P.KLOER,AUTH 2 V.K.BHATIA,D.STAMOU,J.H.HURLEY,P.J.CULLENTITL MOLECULAR INSIGHT INTO VESICLE-TO-TUBULE MEMBRANE REMODELINGTITL 2 BY SNX-BAR PROTEINSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fzt PTK2B crystal structure of pyk2 complexed with pf-4618433 1.95Å AUTH S.HAN,A.MISTRY,J.S.CHANG,D.CUNNINGHAM,M.GRIFFOR,AUTH 2 P.C.BONNETTE,H.WANG,B.A.CHRUNYK,G.E.ASPNES,AUTH 3 D.P.WALKER,A.D.BROSIUS,L.BUCKBINDERTITL STRUCTURAL CHARACTERIZATION OF PROLINE-RICHTITL 2 TYROSINE KINASE 2 (PYK2) REVEALS A UNIQUE (DFG-OUT)TITL 3 CONFORMATION AND ENABLES INHIBITOR DESIGN.REF J.BIOL.CHEM. V. 284 13193 2009REFN ISSN 0021-9258PMID 19244237DOI 10.1074/JBC.M809038200 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3w7r DHODH structure of human dihydroorotate dehydrogenase in complex with mii-4- 097 1.68Å AUTH D.K.INAOKA,M.IIDA,T.TABUCHI,N.LEE,S.HASHIMOTO,S.MATSUOKA,AUTH 2 T.KURANAGA,T.SHIBA,K.SAKAMOTO,S.SUZUKI,E.O.BALOGUN,T.NARA,AUTH 3 T.AOKI,M.INOUE,T.HONMA,A.TANAKA,S.HARADA,K.KITATITL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEXTITL 2 WITH MII-4-097REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3w7r DHODH structure of human dihydroorotate dehydrogenase in complex with mii-4- 097 1.68Å AUTH D.K.INAOKA,M.IIDA,T.TABUCHI,N.LEE,S.HASHIMOTO,S.MATSUOKA,AUTH 2 T.KURANAGA,T.SHIBA,K.SAKAMOTO,S.SUZUKI,E.O.BALOGUN,T.NARA,AUTH 3 T.AOKI,M.INOUE,T.HONMA,A.TANAKA,S.HARADA,K.KITATITL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEXTITL 2 WITH MII-4-097REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3w7r DHODH structure of human dihydroorotate dehydrogenase in complex with mii-4- 097 1.68Å AUTH D.K.INAOKA,M.IIDA,T.TABUCHI,N.LEE,S.HASHIMOTO,S.MATSUOKA,AUTH 2 T.KURANAGA,T.SHIBA,K.SAKAMOTO,S.SUZUKI,E.O.BALOGUN,T.NARA,AUTH 3 T.AOKI,M.INOUE,T.HONMA,A.TANAKA,S.HARADA,K.KITATITL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEXTITL 2 WITH MII-4-097REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2kij ATP7A solution structure of the actuator domain of the copper- transporting atpase atp7a -1.0Å AUTH L.BANCI,I.BERTINI,F.CANTINI,M.MIGLIARDI,G.NATILE,AUTH 2 F.NUSHI,A.ROSATOTITL SOLUTION STRUCTURES OF THE ACTUATOR DOMAIN OF ATP7ATITL 2 AND ATP7B, THE MENKES AND WILSON DISEASE PROTEINSREF BIOCHEMISTRY V. 48 7849 2009REFN ISSN 0006-2960PMID 19645496DOI 10.1021/BI901003K Variant Set Distributions Mapped Variants
General Structure Information 3rl7 DLG1 crytal structure of hdlg1-pdz1 complexed with apc 2.3Å AUTH Z.ZHANG,H.LI,L.CHEN,X.LU,J.ZHANG,P.XU,K.LIN,G.WUTITL MOLECULAR BASIS FOR THE RECOGNITION OF ADENOMATOUS POLYPOSISTITL 2 COLI BY THE DISCS LARGE 1 PROTEIN.REF PLOS ONE V. 6 23507 2011REFN ESSN 1932-6203PMID 21858148DOI 10.1371/JOURNAL.PONE.0023507 Variant Set Distributions Mapped Variants
General Structure Information 3w9y DLG1 crystal structure of the human dlg1 guanylate kinase domain 2.2Å AUTH S.MORI,Y.TEZUKA,A.ARAKAWA,N.HANDA,M.SHIROUZU,T.AKIYAMA,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE GUANYLATE KINASE DOMAIN FROM DISCSTITL 2 LARGE HOMOLOG 1 (DLG1/SAP97)REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 435 334 2013REFN ISSN 0006-291XPMID 23624197DOI 10.1016/J.BBRC.2013.04.056 Variant Set Distributions Mapped Variants
General Structure Information 2v0o FCHO2 fcho2 f-bar domain 2.3Å AUTH W.M.HENNE,H.M.KENT,M.J.G.FORD,B.G.HEDGE,O.DAUMKE,AUTH 2 P.J.BUTLER,R.MITTAL,R.LANGEN,P.R.EVANS,H.T.MCMAHONTITL STRUCTURE AND ANALYSIS OF FCHO2 F-BAR DOMAIN: ATITL 2 DIMERIZING AND MEMBRANE RECRUITMENT MODULE THATTITL 3 EFFECTS MEMBRANE CURVATURE.REF STRUCTURE V. 15 839 2007REFN ISSN 0969-2126PMID 17540576DOI 10.1016/J.STR.2007.05.002 Variant Set Distributions Mapped Variants
General Structure Information 2v0o FCHO2 fcho2 f-bar domain 2.3Å AUTH W.M.HENNE,H.M.KENT,M.J.G.FORD,B.G.HEDGE,O.DAUMKE,AUTH 2 P.J.BUTLER,R.MITTAL,R.LANGEN,P.R.EVANS,H.T.MCMAHONTITL STRUCTURE AND ANALYSIS OF FCHO2 F-BAR DOMAIN: ATITL 2 DIMERIZING AND MEMBRANE RECRUITMENT MODULE THATTITL 3 EFFECTS MEMBRANE CURVATURE.REF STRUCTURE V. 15 839 2007REFN ISSN 0969-2126PMID 17540576DOI 10.1016/J.STR.2007.05.002 Variant Set Distributions Mapped Variants