General Structure Information 3u9j FBXL5 crystal structure of oxidized human fbxl5 hemerythrin like domain 1.6Å AUTH C.SHU,M.W.SUNG,M.D.STEWART,T.I.IGUMENOVA,X.TAN,P.LITITL THE STRUCTURAL BASIS OF IRON SENSING BY THE HUMAN F-BOXTITL 2 PROTEIN FBXL5.REF CHEMBIOCHEM V. 13 788 2012REFN ISSN 1439-4227PMID 22492618DOI 10.1002/CBIC.201200043 Variant Set Distributions Mapped Variants
General Structure Information 4i6j FBXL3 a ubiquitin ligase-substrate complex 2.7Å AUTH W.XING,L.BUSINO,T.R.HINDS,S.T.MARIONNI,N.H.SAIFEE,M.F.BUSH,AUTH 2 M.PAGANO,N.ZHENGTITL SCFFBXL3 UBIQUITIN LIGASE TARGETS CRYPTOCHROMES AT THEIRTITL 2 COFACTOR POCKET.REF NATURE V. 496 64 2013REFN ISSN 0028-0836PMID 23503662DOI 10.1038/NATURE11964 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4im6 NLRP1 lrr domain from human nlrp1 1.65Å Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1fqv SKP2 insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex 2.8Å AUTH B.A.SCHULMAN,A.C.CARRANO,P.D.JEFFREY,Z.BOWEN,AUTH 2 E.R.KINNUCAN,M.S.FINNIN,S.J.ELLEDGE,J.W.HARPER,AUTH 3 M.PAGANO,N.P.PAVLETICHTITL INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THETITL 2 STRUCTURE OF THE SKP1-SKP2 COMPLEX.REF NATURE V. 408 381 2000REFN ISSN 0028-0836PMID 11099048DOI 10.1038/35042620 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 1fqv SKP2 insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex 2.8Å AUTH B.A.SCHULMAN,A.C.CARRANO,P.D.JEFFREY,Z.BOWEN,AUTH 2 E.R.KINNUCAN,M.S.FINNIN,S.J.ELLEDGE,J.W.HARPER,AUTH 3 M.PAGANO,N.P.PAVLETICHTITL INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THETITL 2 STRUCTURE OF THE SKP1-SKP2 COMPLEX.REF NATURE V. 408 381 2000REFN ISSN 0028-0836PMID 11099048DOI 10.1038/35042620 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2ast SKP1 crystal structure of skp1-skp2-cks1 in complex with a p27 peptide 2.3Å AUTH B.HAO,N.ZHENG,B.A.SCHULMAN,G.WU,J.J.MILLER,M.PAGANO,AUTH 2 N.P.PAVLETICHTITL STRUCTURAL BASIS OF THE CKS1-DEPENDENT RECOGNITION OFTITL 2 P27(KIP1) BY THE SCF(SKP2) UBIQUITIN LIGASE.REF MOL.CELL V. 20 9 2005REFN ISSN 1097-2765PMID 16209941DOI 10.1016/J.MOLCEL.2005.09.003 Variant Set Distributions Mapped Variants
General Structure Information 2uzx MET structure of the human receptor tyrosine kinase met in complex with the listeria monocytogenes invasion protein inlb: crystal form i 2.8Å AUTH H.H.NIEMANN,V.JAGER,P.J.G.BUTLER,J.VAN DEN HEUVEL,AUTH 2 S.SCHMIDT,D.FERRARIS,E.GHERARDI,D.W.HEINZTITL STRUCTURE OF THE HUMAN RECEPTOR TYROSINE KINASETITL 2 MET IN COMPLEX WITH THE LISTERIA INVASION PROTEINTITL 3 INLBREF CELL(CAMBRIDGE,MASS.) V. 130 235 2007REFN […]
General Structure Information 4glp CD14 the crystal structure of soluble human cd14 reveals a bent solenoid with a hydrophobic amino-terminal pocket. 4.0Å AUTH S.L.KELLEY,T.LUKK,S.K.NAIR,R.I.TAPPINGTITL THE CRYSTAL STRUCTURE OF HUMAN SOLUBLE CD14 REVEALS A BENTTITL 2 SOLENOID WITH A HYDROPHOBIC AMINO-TERMINAL POCKET.REF J.IMMUNOL. V. 190 1304 2013REFN ISSN 0022-1767PMID 23264655DOI 10.4049/JIMMUNOL.1202446 Variant Set Distributions Ripley’s K […]
General Structure Information 2wfh SLIT2 the human slit 2 dimerization domain d4 1.8Å AUTH E.SEIRADAKE,A.C.VON PHILIPSBORN,M.HENRY,M.FRITZ,AUTH 2 H.LORTAT-JACOB,M.JAMIN,W.HEMRIKA,M.BASTMEYER,S.CUSACK,AUTH 3 A.A.MCCARTHYTITL STRUCTURE AND FUNCTIONAL RELEVANCE OF THE SLIT2TITL 2 HOMODIMERIZATION DOMAIN.REF EMBO REP. V. 10 736 2009REFN ISSN 1469-221XPMID 19498462DOI 10.1038/EMBOR.2009.95 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ulv TLR3 structure of quaternary complex of human tlr3ecd with three fabs (form2) 3.52Å AUTH J.LUO,G.OBMOLOVA,T.J.MALIA,S.J.WU,K.E.DUFFY,J.D.MARION,AUTH 2 J.K.BELL,P.GE,Z.H.ZHOU,A.TEPLYAKOV,Y.ZHAO,R.J.LAMB,AUTH 3 J.L.JORDAN,L.R.SAN MATEO,R.W.SWEET,G.L.GILLILANDTITL LATERAL CLUSTERING OF TLR3:DSRNA SIGNALING UNITS REVEALED BYTITL 2 TLR3ECD:3FABS QUATERNARY STRUCTURE.REF J.MOL.BIOL. V. 421 112 2012REFN ISSN 0022-2836PMID 22579623DOI 10.1016/J.JMB.2012.05.006 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]