General Structure Information
| PDB ID | 4i6j |
| HGNC Gene Label(s) | FBXL3 |
| Structure Name | a ubiquitin ligase-substrate complex |
| Resolution | 2.7Å |
| Reference | AUTH W.XING,L.BUSINO,T.R.HINDS,S.T.MARIONNI,N.H.SAIFEE,M.F.BUSH,AUTH 2 M.PAGANO,N.ZHENGTITL SCFFBXL3 UBIQUITIN LIGASE TARGETS CRYPTOCHROMES AT THEIRTITL 2 COFACTOR POCKET.REF NATURE V. 496 64 2013REFN ISSN 0028-0836PMID 23503662DOI 10.1038/NATURE11964 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 394 |
| Number Of SNVs | 49 |
| Number Of Permutations | 13246 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.044 |
| p-value | 0.743 |
COSMIC
| Number Of Residues | 394 |
| Number Of SNVs | 5 |
| Number Of Permutations | 2721 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.1 |
| p-value | 0.572 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
