General Structure Information 1waw CHIT1 specificity and affinity of natural product cyclopentapeptide inhibitor argadin against human chitinase 1.75Å AUTH F.V.RAO,D.R.HOUSTON,R.G.BOOT,J.M.F.G.AERTS,M.HODKINSON,AUTH 2 D.J.ADAMS,K.SHIOMI,S.OMURA,D.M.F.VAN AALTENTITL SPECIFICITY AND AFFINITY OF NATURAL PRODUCTTITL 2 CYCLOPENTAPEPTIDE INHIBITORS AGAINST ASPERGILLUS FUMIGATUS,TITL 3 HUMAN AND BACTERIAL CHITINASESREF CHEM.BIOL. V. 12 65 2005REFN ISSN 1074-5521PMID 15664516DOI 10.1016/J.CHEMBIOL.2004.10.013 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1waw CHIT1 specificity and affinity of natural product cyclopentapeptide inhibitor argadin against human chitinase 1.75Å AUTH F.V.RAO,D.R.HOUSTON,R.G.BOOT,J.M.F.G.AERTS,M.HODKINSON,AUTH 2 D.J.ADAMS,K.SHIOMI,S.OMURA,D.M.F.VAN AALTENTITL SPECIFICITY AND AFFINITY OF NATURAL PRODUCTTITL 2 CYCLOPENTAPEPTIDE INHIBITORS AGAINST ASPERGILLUS FUMIGATUS,TITL 3 HUMAN AND BACTERIAL CHITINASESREF CHEM.BIOL. V. 12 65 2005REFN ISSN 1074-5521PMID 15664516DOI 10.1016/J.CHEMBIOL.2004.10.013 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 2nyl PPP2R5C crystal structure of protein phosphatase 2a (pp2a) holoenzyme with the catalytic subunit carboxyl terminus truncated 3.8Å AUTH Y.XU,Y.XING,Y.CHEN,Y.CHAO,Z.LIN,E.FAN,J.W.YU,S.STRACK,AUTH 2 P.D.JEFFREY,Y.SHITITL STRUCTURE OF THE PROTEIN PHOSPHATASE 2A HOLOENZYME.REF CELL(CAMBRIDGE,MASS.) V. 127 1239 2006REFN ISSN 0092-8674PMID 17174897DOI 10.1016/J.CELL.2006.11.033 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2nyl PPP2R5C crystal structure of protein phosphatase 2a (pp2a) holoenzyme with the catalytic subunit carboxyl terminus truncated 3.8Å AUTH Y.XU,Y.XING,Y.CHEN,Y.CHAO,Z.LIN,E.FAN,J.W.YU,S.STRACK,AUTH 2 P.D.JEFFREY,Y.SHITITL STRUCTURE OF THE PROTEIN PHOSPHATASE 2A HOLOENZYME.REF CELL(CAMBRIDGE,MASS.) V. 127 1239 2006REFN ISSN 0092-8674PMID 17174897DOI 10.1016/J.CELL.2006.11.033 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4ie2 ARG2 crystal structure of human arginase-2 complexed with inhibitor 1h 2.21Å AUTH A.GOLEBIOWSKI,R.PAUL BECKETT,M.VAN ZANDT,M.K.JI,AUTH 2 D.WHITEHOUSE,T.R.RYDER,E.JAGDMANN,M.ANDREOLI,A.MAZUR,AUTH 3 M.PADMANILAYAM,A.COUSIDO-SIAH,A.MITSCHLER,F.X.RUIZ,AUTH 4 A.PODJARNY,H.SCHROETERTITL 2-SUBSTITUTED-2-AMINO-6-BORONOHEXANOIC ACIDS AS ARGINASETITL 2 INHIBITORS.REF BIOORG.MED.CHEM.LETT. V. 23 2027 2013REFN ISSN 0960-894XPMID 23453840DOI 10.1016/J.BMCL.2013.02.024 Variant Set Distributions Mapped Variants
General Structure Information 3pdf CTSC discovery of novel cyanamide-based inhibitors of cathepsin c 1.85Å AUTH D.LAINE,M.PALOVICH,P.MCCLELAND,E.PETITJEAN,I.DELHOM,H.XIE,AUTH 2 J.DENG,G.LIN,R.DAVIS,A.JOLIT,N.NEVINS,J.VILLA,J.SCHNECKTITL DISCOVERY OF NOVEL CYANAMIDE-BASED INHIBITORS OF CATHEPSIN CREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2zks GZMM structural insights into the proteolytic machinery of apoptosis- inducing granzyme m 2.7Å AUTH L.WU,L.WANG,G.HUA,K.LIU,X.YANG,Y.ZHAI,M.BARTLAM,F.SUN,Z.FANTITL STRUCTURAL BASIS FOR PROTEOLYTIC SPECIFICITY OF THE HUMANTITL 2 APOPTOSIS-INDUCING GRANZYME MREF J.IMMUNOL. V. 183 421 2009REFN ISSN 0022-1767PMID 19542453DOI 10.4049/JIMMUNOL.0803088 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3pbl DRD3 structure of the human dopamine d3 receptor in complex with eticlopride 2.89Å AUTH E.Y.CHIEN,W.LIU,Q.ZHAO,V.KATRITCH,G.W.HAN,M.A.HANSON,L.SHI,AUTH 2 A.H.NEWMAN,J.A.JAVITCH,V.CHEREZOV,R.C.STEVENSTITL STRUCTURE OF THE HUMAN DOPAMINE D3 RECEPTOR IN COMPLEX WITHTITL 2 A D2/D3 SELECTIVE ANTAGONIST.REF SCIENCE V. 330 1091 2010REFN ISSN 0036-8075PMID 21097933DOI 10.1126/SCIENCE.1197410 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1cp3 CASP3 crystal structure of the complex of apopain with the tetrapeptide inhibitor ace-dvad-fmc 2.3Å AUTH P.R.MITTL,S.DI MARCO,J.F.KREBS,X.BAI,D.S.KARANEWSKY,AUTH 2 J.P.PRIESTLE,K.J.TOMASELLI,M.G.GRUTTERTITL STRUCTURE OF RECOMBINANT HUMAN CPP32 IN COMPLEX WITH THETITL 2 TETRAPEPTIDE ACETYL-ASP-VAL-ALA-ASP FLUOROMETHYL KETONE.REF J.BIOL.CHEM. V. 272 6539 1997REFN ISSN 0021-9258PMID 9045680DOI 10.1074/JBC.272.10.6539 Variant Set Distributions Mapped Variants
General Structure Information 3rjm CASP2 caspase2 in complex with chdi ligand 33c 2.55Å AUTH M.C.MAILLARD,F.A.BROOKFIELD,S.M.COURTNEY,F.M.EUSTACHE,AUTH 2 M.J.GEMKOW,R.K.HANDEL,L.C.JOHNSON,P.D.JOHNSON,M.A.KERRY,AUTH 3 F.KRIEGER,M.MENICONI,I.MUNOZ-SANJUAN,J.J.PALFREY,H.PARK,AUTH 4 S.SCHAERTL,M.G.TAYLOR,D.WEDDELL,C.DOMINGUEZTITL EXPLOITING DIFFERENCES IN CASPASE-2 AND -3 S(2) SUBSITES FORTITL 2 SELECTIVITY: STRUCTURE-BASED DESIGN, SOLID-PHASE SYNTHESISTITL 3 AND IN VITRO ACTIVITY OF NOVEL SUBSTRATE-BASED CASPASE-2TITL 4 INHIBITORS.REF BIOORG.MED.CHEM. V. 19 5833 2011REFN ISSN 0968-0896PMID 21903398DOI […]