Assessment of Structural Intolerance and Durability
General Structure Information 2kg5 ARAP3 nmr solution structure of arap3-sam -1.0Å AUTH M.LEONE,J.CELLITTI,M.PELLECCHIATITL THE SAM DOMAIN OF THE LIPID PHOSPHATASE SHIP2TITL 2 ADOPTS A COMMON MODEL TO INTERACT WITH ARAP3-SAMTITL 3 AND EPHA2-SAM.REF BMC STRUCT.BIOL. V. 9 59 2009REFN ESSN 1472-6807PMID 19765305DOI 10.1186/1472-6807-9-59 Variant Set Distributions Mapped Variants
General Structure Information 3a98 DOCK2 crystal structure of the complex of the interacting regions of dock2 and elmo1 2.1Å AUTH K.HANAWA-SUETSUGU,M.KUKIMOTO-NIINO,C.MISHIMA-TSUMAGARI,AUTH 2 R.AKASAKA,N.OHSAWA,S.SEKINE,T.ITO,N.TOCHIO,S.KOSHIBA,AUTH 3 T.KIGAWA,T.TERADA,M.SHIROUZU,D.KOHDA,A.NISHIKIMI,Y.FUKUI,AUTH 4 S.YOKOYAMATITL STRUCTURAL BASIS OF FUNCTIONAL COMPLEX FORMATION BETWEENTITL 2 DOCK2 AND ELMO1 FOR RAC ACTIVATION IN LYMPHOCYTE CHEMOTAXISREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3a98 ELMO1 crystal structure of the complex of the interacting regions of dock2 and elmo1 2.1Å AUTH K.HANAWA-SUETSUGU,M.KUKIMOTO-NIINO,C.MISHIMA-TSUMAGARI,AUTH 2 R.AKASAKA,N.OHSAWA,S.SEKINE,T.ITO,N.TOCHIO,S.KOSHIBA,AUTH 3 T.KIGAWA,T.TERADA,M.SHIROUZU,D.KOHDA,A.NISHIKIMI,Y.FUKUI,AUTH 4 S.YOKOYAMATITL STRUCTURAL BASIS OF FUNCTIONAL COMPLEX FORMATION BETWEENTITL 2 DOCK2 AND ELMO1 FOR RAC ACTIVATION IN LYMPHOCYTE CHEMOTAXISREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 1tdh NEIL1 crystal structure of human endonuclease viii-like 1 (neil1) 2.1Å AUTH S.DOUBLIE,V.BANDARU,J.P.BOND,S.S.WALLACETITL THE CRYSTAL STRUCTURE OF HUMAN ENDONUCLEASETITL 2 VIII-LIKE 1 (NEIL1) REVEALS A ZINCLESS FINGERTITL 3 MOTIF REQUIRED FOR GLYCOSYLASE ACTIVITY.REF PROC.NATL.ACAD.SCI.USA V. 101 10284 2004REFN ISSN 0027-8424PMID 15232006DOI 10.1073/PNAS.0402051101 Variant Set Distributions Mapped Variants
General Structure Information 2hm2 PYDC1 solution structure of asc2 -1.0Å AUTH A.NATARAJAN,R.GHOSE,J.M.HILLTITL STRUCTURE AND DYNAMICS OF ASC2, A PYRINTITL 2 DOMAIN-ONLY PROTEIN THAT REGULATES INFLAMMATORYTITL 3 SIGNALINGREF J.BIOL.CHEM. V. 281 31863 2006REFN ISSN 0021-9258PMID 16905547DOI 10.1074/JBC.M605458200 Variant Set Distributions Mapped Variants
General Structure Information 3ec8 RADIL the crystal structure of the ra domain of flj10324 (radil) 2.6Å AUTH M.WISNIEWSKA,L.LEHTIO,J.ANDERSSON,C.H.ARROWSMITH,R.COLLINS,AUTH 2 L.G.DAHLGREN,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTENYOVA,M.MOCHE,M.E.NILSSON,P.NORDLUND,T.NYMAN,K.OLESEN,AUTH 5 C.PERSSON,J.SAGEMARK,H.SCHUELER,A.G.THORSELL,L.TRESAUGUES,AUTH 6 S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WIKSTROM,H.BERGLUNDTITL THE CRYSTAL STRUCTURE OF THE RA DOMAIN OF FLJ10324 (RADIL)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 1mp1 SRRM1 solution structure of the pwi motif from srm160 -1.0Å AUTH B.R.SZYMCZYNA,J.BOWMAN,S.MCCRACKEN,A.PINEDA-LUCENA,AUTH 2 Y.LU,B.COX,M.LAMBERMON,B.R.GRAVELEY,C.H.ARROWSMITH,AUTH 3 B.J.BLENCOWETITL STRUCTURE AND FUNCTION OF THE PWI MOTIF: A NOVELTITL 2 NUCLEIC ACID-BINDING DOMAIN THAT FACILITATESTITL 3 PRE-MRNA PROCESSING.REF GENES DEV. V. 17 461 2003REFN ISSN 0890-9369PMID 12600940DOI 10.1101/GAD.1060403 Variant Set Distributions Mapped Variants
General Structure Information 3ihj GPT2 human alanine aminotransferase 2 in complex with plp 2.3Å AUTH M.WISNIEWSKA,M.I.SIPONEN,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 C.BOUNTRA,R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTENYOVA,A.KOTZSCH,M.MOCHE,T.K.NIELSEN,P.NORDLUND,AUTH 5 T.NYMAN,C.PERSSON,A.K.ROOS,P.SCHUTZ,L.SVENSSON,A.G.THORSELL,AUTH 6 L.TRESAUGUES,S.VAN DEN BERG,J.WEIGELT,M.WELIN,H.SCHULERTITL HUMAN GLUTAMATE PYRUVATE TRANSAMINASE 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dnx STX12 solution structure of rsgi ruh-063, an n-terminal domain of syntaxin 12 from human cdna -1.0Å AUTH T.ABE,H.HIROTA,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-063, AN N-TERMINALTITL 2 DOMAIN OF SYNTAXIN 12 FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2lt7 ZBTB33 solution nmr structure of kaiso zinc finger dna binding domain in complex with kaiso binding site dna -1.0Å AUTH B.A.BUCK-KOEHNTOP,R.L.STANFIELD,D.C.EKIERT,AUTH 2 M.A.MARTINEZ-YAMOUT,H.J.DYSON,I.A.WILSON,P.E.WRIGHTTITL MOLECULAR BASIS FOR RECOGNITION OF METHYLATED AND SPECIFICTITL 2 DNA SEQUENCES BY THE ZINC FINGER PROTEIN KAISO.REF PROC.NATL.ACAD.SCI.USA V. 109 15229 2012REFN ISSN 0027-8424PMID 22949637DOI 10.1073/PNAS.1213726109 Variant Set […]