Assessment of Structural Intolerance and Durability
General Structure Information 2z0v SH3GL3 crystal structure of bar domain of endophilin-iii 2.49Å AUTH K.MURAYAMA,M.KATO-MURAYAMA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF BAR DOMAIN OF ENDOPHILIN-IIIREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1d5v FOXC2 solution structure of the forkhead domain of the adipocyte- transcription factor freac-11 (s12) -1.0Å AUTH M.J.VAN DONGEN,A.CEDERBERG,P.CARLSSON,S.ENERBACK,AUTH 2 M.WIKSTROMTITL SOLUTION STRUCTURE AND DYNAMICS OF THE DNA-BINDINGTITL 2 DOMAIN OF THE ADIPOCYTE-TRANSCRIPTION FACTORTITL 3 FREAC-11.REF J.MOL.BIOL. V. 296 351 2000REFN ISSN 0022-2836PMID 10669593DOI 10.1006/JMBI.1999.3476 Variant Set Distributions Mapped Variants
General Structure Information 2l4m ZBP1 solution structure of the zbeta domain of human dai and its binding modes to b- and z-dna -1.0Å AUTH K.KIM,B.KHAYRUTDINOV,C.-K.LEE,H.-K.CHEONG,S.KANG,H.PARK,AUTH 2 S.LEE,Y.-G.KIM,J.-G.JEE,A.RICH,K.K.KIM,Y.H.JEONTITL SOLUTION STRUCTURE OF THE ZBETA DOMAIN OF HUMANTITL 2 DNA-DEPENDENT ACTIVATOR OF IFN-REGULATORY FACTORS AND ITSTITL 3 BINDING MODES TO B- AND Z-DNAREF PROC.NATL.ACAD.SCI.USA 2011REFN ESSN 1091-6490 Variant […]
General Structure Information 3qf2 NLRP3 crystal structure of nalp3 pyd 1.7Å AUTH J.Y.BAE,H.H.PARKTITL CRYSTAL STRUCTURE OF NALP3 PROTEIN PYRIN DOMAIN (PYD) ANDTITL 2 ITS IMPLICATIONS IN INFLAMMASOME ASSEMBLYREF J.BIOL.CHEM. V. 286 39528 2011REFN ISSN 0021-9258PMID 21880711DOI 10.1074/JBC.M111.278812 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1wyn CNN2 solution structure of the ch domain of human calponin-2 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN OF HUMANTITL 2 CALPONIN-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4nac RPRD1A crystal structure of the n-terminal domain of p15rs 2.0Å AUTH K.MEI,Z.JIN,F.REN,Y.WANG,Z.CHANG,X.WANGTITL CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF P15RSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l9s PHF12 solution structure of pf1 sid1-msin3a pah2 complex -1.0Å AUTH G.S.KUMAR,T.XIE,Y.ZHANG,I.RADHAKRISHNANTITL SOLUTION STRUCTURE OF THE MSIN3A PAH2-PF1 SID1 COMPLEX: ATITL 2 MAD1/MXD1-LIKE INTERACTION DISRUPTED BY MRG15 IN THETITL 3 RPD3S/SIN3S COMPLEX.REF J.MOL.BIOL. V. 408 987 2011REFN ISSN 0022-2836PMID 21440557DOI 10.1016/J.JMB.2011.03.043 Variant Set Distributions Mapped Variants
General Structure Information 2xv4 POLR3C structure of human rpc62 (partial) 2.95Å AUTH S.LEFEVRE,H.DUMAY-ODELOT,L.EL AYOUBI,A.BUDD,P.LEGRAND,AUTH 2 N.PINAUD,M.TEICHMANN,S.FRIBOURGTITL STRUCTURE-FUNCTION ANALYSIS OF HRPC62 PROVIDES INSIGHTSTITL 2 INTO RNA POLYMERASE III TRANSCRIPTIONREF NAT.STRUCT.MOL.BIOL. V. 18 352 2011REFN ISSN 1545-9993PMID 21358628DOI 10.1038/NSMB.1996 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4ldq MRI1 crystal structure of the mediator of rho dependent invasion 2.5Å AUTH P.D.TEMPLETON,E.S.LITMAN,S.I.METZNER,N.G.AHN,M.C.SOUSATITL STRUCTURE OF MEDIATOR OF RHOA-DEPENDENT INVASION (MRDI)TITL 2 EXPLAINS ITS DUAL FUNCTION AS A METABOLIC ENZYME AND ATITL 3 MEDIATOR OF CELL INVASION.REF BIOCHEMISTRY V. 52 5675 2013REFN ISSN 0006-2960PMID 23859498DOI 10.1021/BI400556E Variant Set Distributions Mapped Variants
General Structure Information 3c5r BARD1 crystal structure of the bard1 ankyrin repeat domain and its functional consequences 2.0Å AUTH D.FOX,I.LE TRONG,P.RAJAGOPAL,P.S.BRZOVIC,R.E.STENKAMP,AUTH 2 R.E.KLEVITTITL CRYSTAL STRUCTURE OF THE BARD1 ANKYRIN REPEAT DOMAIN AND ITSTITL 2 FUNCTIONAL CONSEQUENCES.REF J.BIOL.CHEM. V. 283 21179 2008REFN ISSN 0021-9258PMID 18480049DOI 10.1074/JBC.M802333200 Variant Set Distributions Mapped Variants