General Structure Information
| PDB ID | 2xv4 |
| HGNC Gene Label(s) | POLR3C |
| Structure Name | structure of human rpc62 (partial) |
| Resolution | 2.95Å |
| Reference | AUTH S.LEFEVRE,H.DUMAY-ODELOT,L.EL AYOUBI,A.BUDD,P.LEGRAND,AUTH 2 N.PINAUD,M.TEICHMANN,S.FRIBOURGTITL STRUCTURE-FUNCTION ANALYSIS OF HRPC62 PROVIDES INSIGHTSTITL 2 INTO RNA POLYMERASE III TRANSCRIPTIONREF NAT.STRUCT.MOL.BIOL. V. 18 352 2011REFN ISSN 1545-9993PMID 21358628DOI 10.1038/NSMB.1996 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 399 |
| Number Of SNVs | 104 |
| Number Of Permutations | 56057 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.024 |
| p-value | 0.805 |
COSMIC
| Number Of Residues | 399 |
| Number Of SNVs | 5 |
| Number Of Permutations | 419 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.1 |
| p-value | 0.227 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 104 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.293 |
| p-value | 0.162 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
