3GD8.A | AQP4

General Structure Information 3gd8 AQP4 crystal structure of human aquaporin 4 at 1.8 and its mechanism of conductance 1.8Å AUTH J.D.HO,R.YEH,A.SANDSTROM,I.CHORNY,W.E.HARRIES,R.A.ROBBINS,AUTH 2 L.J.MIERCKE,R.M.STROUDTITL CRYSTAL STRUCTURE OF HUMAN AQUAPORIN 4 AT 1.8 A AND ITSTITL 2 MECHANISM OF CONDUCTANCE.REF PROC.NATL.ACAD.SCI.USA V. 106 7437 2009REFN ISSN 0027-8424PMID 19383790DOI 10.1073/PNAS.0902725106 Variant Set Distributions Mapped Variants

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2BBA.A | EPHB4

General Structure Information 2bba EPHB4 crystal structure and thermodynamic characterization of the ephb4 receptor in complex with an ephrin-b2 antagonist peptide reveals the determinants for receptor specificity. 1.65Å AUTH J.E.CHRENCIK,A.BROOUN,M.I.RECHT,M.L.KRAUS,M.KOOLPE,AUTH 2 A.R.KOLATKAR,R.H.BRUCE,G.MARTINY-BARON,H.WIDMER,AUTH 3 E.B.PASQUALE,P.KUHNTITL STRUCTURE AND THERMODYNAMIC CHARACTERIZATION OF THETITL 2 EPHB4/EPHRIN-B2 ANTAGONIST PEPTIDE COMPLEX REVEALS THETITL 3 DETERMINANTS FOR RECEPTOR SPECIFICITY.REF STRUCTURE V. 14 […]

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2HLE.B | EFNB2

General Structure Information 2hle EFNB2 structural and biophysical characterization of the ephb4-ephrinb2 protein protein interaction and receptor specificity. 2.05Å AUTH J.E.CHRENCIK,A.BROOUN,M.L.KRAUS,M.I.RECHT,A.R.KOLATKAR,AUTH 2 G.W.HAN,J.M.SEIFERT,H.WIDMER,M.AUER,P.KUHNTITL STRUCTURAL AND BIOPHYSICAL CHARACTERIZATION OF THETITL 2 EPHB4-EPHRINB2 PROTEIN-PROTEIN INTERACTION AND RECEPTORTITL 3 SPECIFICITY.REF J.BIOL.CHEM. V. 281 28185 2006REFN ISSN 0021-9258PMID 16867992DOI 10.1074/JBC.M605766200 Variant Set Distributions Mapped Variants

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2QNK.A | HAAO

General Structure Information 2qnk HAAO crystal structure of human 3-hydroxyanthranilate 3,4-dioxygenase 1.6Å AUTH E.BITTO,C.A.BINGMAN,G.E.WESENBERG,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF HUMAN 3-HYDROXYANTHRANILATETITL 2 3,4-DIOXYGENASE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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4FSV.A | HSPA2

General Structure Information 4fsv HSPA2 crystal structure of a heat shock 70kda protein 2 (hspa2) from homo sapiens at 1.80 a resolution 1.8Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL CRYSTAL STRUCTURE OF A HEAT SHOCK 70KDA PROTEIN 2 (HSPA2)TITL 2 FROM HOMO SAPIENS AT 1.80 A RESOLUTIONREF TO […]

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2G2B.A | AIF1

General Structure Information 2g2b AIF1 nmr structure of the human allograft inflammatory factor 1 -1.0Å AUTH J.SONG,R.C.TYLER,C.L.NEWMAN,D.VINAROV,J.L.MARKLEYTITL NMR STRUCTURE OF THE HUMAN ALLOGRAFT INFLAMMATORYTITL 2 FACTOR 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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3PBL.B | DRD3

General Structure Information 3pbl DRD3 structure of the human dopamine d3 receptor in complex with eticlopride 2.89Å AUTH E.Y.CHIEN,W.LIU,Q.ZHAO,V.KATRITCH,G.W.HAN,M.A.HANSON,L.SHI,AUTH 2 A.H.NEWMAN,J.A.JAVITCH,V.CHEREZOV,R.C.STEVENSTITL STRUCTURE OF THE HUMAN DOPAMINE D3 RECEPTOR IN COMPLEX WITHTITL 2 A D2/D3 SELECTIVE ANTAGONIST.REF SCIENCE V. 330 1091 2010REFN ISSN 0036-8075PMID 21097933DOI 10.1126/SCIENCE.1197410 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]

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2I3C.A | ASPA

General Structure Information 2i3c ASPA crystal structure of an aspartoacylase from homo sapiens 2.8Å AUTH E.BITTO,C.A.BINGMAN,G.E.WESENBERG,J.G.MCCOY,AUTH 2 G.N.PHILLIPSTITL STRUCTURE OF ASPARTOACYLASE, THE BRAIN ENZYMETITL 2 IMPAIRED IN CANAVAN DISEASE.REF PROC.NATL.ACAD.SCI.USA V. 104 456 2007REFN ISSN 0027-8424PMID 17194761DOI 10.1073/PNAS.0607817104 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants

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2RGZ.A | HMOX2

General Structure Information 2rgz HMOX2 ensemble refinement of the protein crystal structure of human heme oxygenase-2 c127a (ho-2) with bound heme 2.61Å AUTH C.M.BIANCHETTI,L.YI,S.W.RAGSDALE,G.N.PHILLIPS JR.TITL COMPARISON OF APO- AND HEME-BOUND CRYSTAL STRUCTURES OF ATITL 2 TRUNCATED HUMAN HEME OXYGENASE-2.REF J.BIOL.CHEM. V. 282 37624 2007REFN ISSN 0021-9258PMID 17965015DOI 10.1074/JBC.M707396200 Variant Set Distributions Mapped Variants

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3US4.A | MATK

General Structure Information 3us4 MATK crystal structure of a sh2 domain of a megakaryocyte-associated tyrosine kinase (matk) from homo sapiens at 1.50 a resolution 1.5Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL CRYSTAL STRUCTURE OF A SH2 DOMAIN OF ATITL 2 MEGAKARYOCYTE-ASSOCIATED TYROSINE KINASE (MATK) FROM HOMOTITL 3 SAPIENS […]

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