General Structure Information
| PDB ID | 2qnk |
| HGNC Gene Label(s) | HAAO |
| Structure Name | crystal structure of human 3-hydroxyanthranilate 3,4-dioxygenase |
| Resolution | 1.6Å |
| Reference | AUTH E.BITTO,C.A.BINGMAN,G.E.WESENBERG,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF HUMAN 3-HYDROXYANTHRANILATETITL 2 3,4-DIOXYGENASE.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 278 |
| Number Of SNVs | 72 |
| Number Of Permutations | 35561 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.029 |
| p-value | 0.34 |
COSMIC
| Number Of Residues | 278 |
| Number Of SNVs | 3 |
| Number Of Permutations | 108 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.667 |
| p-value | 0.567 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 72 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.46 |
| p-value | 0.587 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
