Assessment of Structural Intolerance and Durability
General Structure Information 3ihr UCHL5 crystal structure of uch37 2.95Å AUTH S.E.BURGIE,C.A.BINGMAN,A.B.SONI,G.N.PHILLIPSTITL STRUCTURAL CHARACTERIZATION OF HUMAN UCH37.REF PROTEINS 2011REFN ESSN 1097-0134PMID 21953935DOI 10.1002/PROT.23147 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2lgr OARD1 solution structure of human protein c6orf130, a putative macro domain -1.0Å AUTH F.C.PETERSON,D.CHEN,B.L.LYTLE,M.N.ROSSI,I.AHEL,J.M.DENU,AUTH 2 B.F.VOLKMANTITL ORPHAN MACRODOMAIN PROTEIN (HUMAN C6ORF130) IS ANTITL 2 O-ACYL-ADP-RIBOSE DEACYLASE: SOLUTION STRUCTURE ANDTITL 3 CATALYTIC PROPERTIES.REF J.BIOL.CHEM. V. 286 35955 2011REFN ISSN 0021-9258PMID 21849506DOI 10.1074/JBC.M111.276238 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3ue2 PUF60 crystal structure of a rna binding domain of poly-u binding splicing factor 60kda (puf60) from homo sapiens at 1.23 a resolution 1.23Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGYTITL CRYSTAL STRUCTURE OF A RNA BINDING DOMAIN OF POLY-U BINDINGTITL 2 SPLICING FACTOR 60KDA (PUF60) FROM […]
General Structure Information 3hd6 RHCG crystal structure of the human rhesus glycoprotein rhcg 2.1Å AUTH F.GRUSWITZ,S.CHAUDHARY,J.D.HO,A.SCHLESSINGER,B.PEZESHKI,AUTH 2 C.M.HO,A.SALI,C.M.WESTHOFF,R.M.STROUDTITL FUNCTION OF HUMAN RH BASED ON STRUCTURE OF RHCG AT 2.1 A.REF PROC.NATL.ACAD.SCI.USA V. 107 9638 2010REFN ISSN 0027-8424PMID 20457942DOI 10.1073/PNAS.1003587107 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2h1s GRHPR crystal structure of a glyoxylate/hydroxypyruvate reductase from homo sapiens 2.45Å AUTH E.BITTO,G.E.WESENBERG,G.N.PHILLIPS JR.,C.A.BINGMAN,AUTH 2 CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS (CESG)TITL CRYSTAL STRUCTURE OF A GLYOXYLATE/HYDROXYPYRUVATE REDUCTASETITL 2 FROM HOMO SAPIENSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1wi1 CADPS solution structure of the ph domain of human calcium- dependent activator protein for secretion (caps) -1.0Å AUTH M.YONEYAMA,K.IZUMI,M.YOSHIDA,N.TOCHIO,S.KOSHIBA,AUTH 2 M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF HUMANTITL 2 CALCIUM-DEPENDENT ACTIVATOR PROTEIN FOR SECRETIONTITL 3 (CAPS)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kt0 NANOG solution structure of human stem cell transcription factor nanog homeodomain fragment -1.0Å AUTH S.C.SAHU,J.L.MARKLEYTITL SOLUTION STRUCTURE OF HUMAN STEM CELL TRANSCRIPTION FACTORTITL 2 NANOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ab1 AAMDC x-ray structure of gene product from homo sapiens hs.95870 2.59Å AUTH CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS (CESG)TITL X-RAY STRUCTURE OF GENE PRODUCT FROM HOMO SAPIENS HS.95870REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2q4k C11orf68 ensemble refinement of the protein crystal structure of gene product from homo sapiens hs.433573 2.5Å AUTH E.J.LEVIN,D.A.KONDRASHOV,G.E.WESENBERG,G.N.PHILLIPSTITL ENSEMBLE REFINEMENT OF PROTEIN CRYSTAL STRUCTURES:TITL 2 VALIDATION AND APPLICATION.REF STRUCTURE V. 15 1040 2007REFN ISSN 0969-2126PMID 17850744DOI 10.1016/J.STR.2007.06.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4iej DMAP1 crystal structure of a dna methyltransferase 1 associated protein 1 (dmap1) from homo sapiens at 1.45 a resolution 1.45Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGYTITL CRYSTAL STRUCTURE OF A DNA METHYLTRANSFERASE 1 ASSOCIATEDTITL 2 PROTEIN 1 (DMAP1) FROM HOMO SAPIENS AT 1.45 A RESOLUTIONREF […]