Assessment of Structural Intolerance and Durability
General Structure Information 1k93 CALM3 crystal structure of the adenylyl cyclase domain of anthrax edema factor (ef) in complex with calmodulin 2.95Å AUTH C.L.DRUM,S.-Z.YAN,J.BARD,Y.-Q.SHEN,D.LU,AUTH 2 S.SOELAIMAN,Z.GRABAREK,A.BOHM,W.-J.TANGTITL STRUCTURAL BASIS FOR THE ACTIVATION OF ANTHRAXTITL 2 ADENYLYL CYCLASE EXOTOXIN BY CALMODULIN.REF NATURE V. 415 396 2002REFN ISSN 0028-0836PMID 11807546DOI 10.1038/415396A Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1k93 CALM2 crystal structure of the adenylyl cyclase domain of anthrax edema factor (ef) in complex with calmodulin 2.95Å AUTH C.L.DRUM,S.-Z.YAN,J.BARD,Y.-Q.SHEN,D.LU,AUTH 2 S.SOELAIMAN,Z.GRABAREK,A.BOHM,W.-J.TANGTITL STRUCTURAL BASIS FOR THE ACTIVATION OF ANTHRAXTITL 2 ADENYLYL CYCLASE EXOTOXIN BY CALMODULIN.REF NATURE V. 415 396 2002REFN ISSN 0028-0836PMID 11807546DOI 10.1038/415396A Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1k93 CALM1 crystal structure of the adenylyl cyclase domain of anthrax edema factor (ef) in complex with calmodulin 2.95Å AUTH C.L.DRUM,S.-Z.YAN,J.BARD,Y.-Q.SHEN,D.LU,AUTH 2 S.SOELAIMAN,Z.GRABAREK,A.BOHM,W.-J.TANGTITL STRUCTURAL BASIS FOR THE ACTIVATION OF ANTHRAXTITL 2 ADENYLYL CYCLASE EXOTOXIN BY CALMODULIN.REF NATURE V. 415 396 2002REFN ISSN 0028-0836PMID 11807546DOI 10.1038/415396A Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1a3q NFKB2 human nf-kappa-b p52 bound to dna 2.1Å AUTH P.CRAMER,C.J.LARSON,G.L.VERDINE,C.W.MULLERTITL STRUCTURE OF THE HUMAN NF-KAPPAB P52 HOMODIMER-DNATITL 2 COMPLEX AT 2.1 A RESOLUTION.REF EMBO J. V. 16 7078 1997REFN ISSN 0261-4189PMID 9384586DOI 10.1093/EMBOJ/16.23.7078 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4my2 NDP crystal structure of norrin in fusion with maltose binding protein 2.4Å AUTH J.KE,K.G.HARIKUMAR,C.ERICE,C.CHEN,X.GU,L.WANG,N.PARKER,AUTH 2 Z.CHENG,W.XU,B.O.WILLIAMS,K.MELCHER,L.J.MILLER,H.E.XUTITL STRUCTURE AND FUNCTION OF NORRIN IN ASSEMBLY AND ACTIVATIONTITL 2 OF A FRIZZLED 4-LRP5/6 COMPLEX.REF GENES DEV. V. 27 2305 2013REFN ISSN 0890-9369PMID 24186977DOI 10.1101/GAD.228544.113 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1vyh PAFAH1B2 paf-ah holoenzyme: lis1/alfa2 3.4Å AUTH C.TARRICONE,F.PERRINA,S.MONZANI,L.MASSIMILIANO,AUTH 2 M.H.KIM,Z.S.DEREWENDA,S.KNAPP,L.-H.TSAI,A.MUSACCHIOTITL COUPLING PAF SIGNALING TO DYNEIN REGULATION:TITL 2 STRUCTURE OF LIS1 IN COMPLEX WITH PAF-TITL 3 ACETYLHYDROLASE.REF NEURON V. 44 809 2004REFN ISSN 0896-6273PMID 15572112DOI 10.1016/J.NEURON.2004.11.019 Variant Set Distributions Mapped Variants
General Structure Information 3cpf EIF5A crystal structure of human eukaryotic translation initiation factor eif5a 2.5Å AUTH Y.TONG,I.PARK,B.S.HONG,L.NEDYALKOVA,W.TEMPEL,H.W.PARKTITL CRYSTAL STRUCTURE OF HUMAN EIF5A1: INSIGHT INTO FUNCTIONALTITL 2 SIMILARITY OF HUMAN EIF5A1 AND EIF5A2.REF PROTEINS V. 75 1040 2009REFN ISSN 0887-3585PMID 19280598DOI 10.1002/PROT.22378 Variant Set Distributions Mapped Variants
General Structure Information 2zu6 EIF4A1 crystal structure of the eif4a-pdcd4 complex 2.8Å AUTH J.H.CHANG,Y.H.CHO,S.Y.SOHN,J.M.CHOI,A.KIM,Y.C.KIM,AUTH 2 S.K.JANG,Y.CHOTITL CRYSTAL STRUCTURE OF THE EIF4A-PDCD4 COMPLEXREF PROC.NATL.ACAD.SCI.USA V. 106 3148 2009REFN ISSN 0027-8424PMID 19204291DOI 10.1073/PNAS.0808275106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4li0 RAB8A crystal structure of gdp-bound rab8:grab 3.3Å AUTH Z.GUO,X.HOU,R.S.GOODY,A.ITZENTITL INTERMEDIATES IN THE GUANINE NUCLEOTIDE EXCHANGE REACTION OFTITL 2 RAB8 PROTEIN CATALYZED BY GUANINE NUCLEOTIDE EXCHANGETITL 3 FACTORS RABIN8 AND GRAB.REF J.BIOL.CHEM. V. 288 32466 2013REFN ISSN 0021-9258PMID 24072714DOI 10.1074/JBC.M113.498329 Variant Set Distributions Mapped Variants
General Structure Information 1h95 YBX1 solution structure of the single-stranded dna-binding cold shock domain (csd) of human y-box protein 1 (yb1) determined by nmr (10 lowest energy structures) -1.0Å AUTH C.P.A.M.KLOKS,C.A.E.M.SPRONK,E.LASONDER,A.HOFFMANN,AUTH 2 G.W.VUISTER,S.GRZESIEK,C.W.HILBERSTITL THE SOLUTION STRUCTURE AND DNA-BINDING PROPERTIESTITL 2 OF THE COLD-SHOCK DOMAIN OF THE HUMAN Y-BOXTITL 3 PROTEIN YB-1.REF J.MOL.BIOL. V. 316 317 […]