General Structure Information
| PDB ID | 2zu6 |
| HGNC Gene Label(s) | EIF4A1 |
| Structure Name | crystal structure of the eif4a-pdcd4 complex |
| Resolution | 2.8Å |
| Reference | AUTH J.H.CHANG,Y.H.CHO,S.Y.SOHN,J.M.CHOI,A.KIM,Y.C.KIM,AUTH 2 S.K.JANG,Y.CHOTITL CRYSTAL STRUCTURE OF THE EIF4A-PDCD4 COMPLEXREF PROC.NATL.ACAD.SCI.USA V. 106 3148 2009REFN ISSN 0027-8424PMID 19204291DOI 10.1073/PNAS.0808275106 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 344 |
| Number Of SNVs | 18 |
| Number Of Permutations | 10837 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.02 |
| p-value | 0.944 |
COSMIC
| Number Of Residues | 344 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 18 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | -0.405 |
| p-value | 0.241 |