Assessment of Structural Intolerance and Durability
General Structure Information 3ahr ERO1L inactive human ero1 3.07Å AUTH K.INABA,S.MASUI,H.IIDA,S.VAVASSORI,R.SITIA,M.SUZUKITITL CRYSTAL STRUCTURES OF HUMAN ERO1-ALPHA REVEAL THE MECHANISMSTITL 2 OF REGULATED AND TARGETED OXIDATION OF PDIREF EMBO J. V. 29 3330 2010REFN ISSN 0261-4189PMID 20834232DOI 10.1038/EMBOJ.2010.222 Variant Set Distributions Mapped Variants
General Structure Information 3aqg ZG16B crystal structure of human pancreatic secretory protein zg16b 2.75Å AUTH M.KANAGAWA,T.SATOH,A.IKEDA,Y.NAKANO,H.YAGI,K.KATO,AUTH 2 K.KOJIMA-AIKAWA,Y.YAMAGUCHITITL CRYSTAL STRUCTURES OF HUMAN SECRETORY PROTEINS ZG16P ANDTITL 2 ZG16B REVEAL A JACALIN-RELATED BETA-PRISM FOLDREF BIOCHEM.BIOPHYS.RES.COMMUN. 2010REFN ESSN 1090-2104PMID 21110947DOI 10.1016/J.BBRC.2010.11.093 Variant Set Distributions Mapped Variants
General Structure Information 3evi PDCL2 crystal structure of the thioredoxin-fold domain of human phosducin- like protein 2 2.7Å AUTH X.LOU,R.BAO,C.Z.ZHOU,Y.CHENTITL STRUCTURE OF THE THIOREDOXIN-FOLD DOMAIN OF HUMANTITL 2 PHOSDUCIN-LIKE PROTEIN 2REF ACTA CRYSTALLOGR.,SECT.F V. 65 67 2009REFN ESSN 1744-3091PMID 19193988DOI 10.1107/S1744309108037342 Variant Set Distributions Mapped Variants
General Structure Information 1u6g CAND1 crystal structure of the cand1-cul1-roc1 complex 3.1Å AUTH S.J.GOLDENBERG,T.C.CASCIO,S.D.SHUMWAY,K.C.GARBUTT,AUTH 2 J.LIU,Y.XIONG,N.ZHENGTITL STRUCTURE OF THE CAND1-CUL1-ROC1 COMPLEX REVEALSTITL 2 REGULATORY MECHANISMS FOR THE ASSEMBLY OF THETITL 3 MULTISUBUNIT CULLIN-DEPENDENT UBIQUITIN LIGASESREF CELL(CAMBRIDGE,MASS.) V. 119 517 2004REFN ISSN 0092-8674PMID 15537541DOI 10.1016/J.CELL.2004.10.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 3av1 HIST2H3A the human nucleosome structure containing the histone variant h3.2 2.5Å AUTH H.TACHIWANA,A.OSAKABE,T.SHIGA,Y.MIYA,H.KIMURA,W.KAGAWA,AUTH 2 H.KURUMIZAKATITL STRUCTURES OF HUMAN NUCLEOSOMES CONTAINING MAJOR HISTONE H3TITL 2 VARIANTSREF ACTA CRYSTALLOGR.,SECT.D V. 67 578 2011REFN ISSN 0907-4449PMID 21636898DOI 10.1107/S0907444911014818 Variant Set Distributions Mapped Variants
General Structure Information 3av1 HIST2H3C the human nucleosome structure containing the histone variant h3.2 2.5Å AUTH H.TACHIWANA,A.OSAKABE,T.SHIGA,Y.MIYA,H.KIMURA,W.KAGAWA,AUTH 2 H.KURUMIZAKATITL STRUCTURES OF HUMAN NUCLEOSOMES CONTAINING MAJOR HISTONE H3TITL 2 VARIANTSREF ACTA CRYSTALLOGR.,SECT.D V. 67 578 2011REFN ISSN 0907-4449PMID 21636898DOI 10.1107/S0907444911014818 Variant Set Distributions Mapped Variants
General Structure Information 3av1 HIST2H3D the human nucleosome structure containing the histone variant h3.2 2.5Å AUTH H.TACHIWANA,A.OSAKABE,T.SHIGA,Y.MIYA,H.KIMURA,W.KAGAWA,AUTH 2 H.KURUMIZAKATITL STRUCTURES OF HUMAN NUCLEOSOMES CONTAINING MAJOR HISTONE H3TITL 2 VARIANTSREF ACTA CRYSTALLOGR.,SECT.D V. 67 578 2011REFN ISSN 0907-4449PMID 21636898DOI 10.1107/S0907444911014818 Variant Set Distributions Mapped Variants
General Structure Information 3e9l PRPF8 crystal structure of human prp8, residues 1755-2016 1.95Å AUTH V.PENA,A.ROZOV,P.FABRIZIO,R.LUHRMANN,M.C.WAHLTITL STRUCTURE AND FUNCTION OF AN RNASE H DOMAIN AT THE HEART OFTITL 2 THE SPLICEOSOME.REF EMBO J. V. 27 2929 2008REFN ISSN 0261-4189PMID 18843295DOI 10.1038/EMBOJ.2008.209 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4hon KDM4D crystal structure of human jmjd2d/kdm4d in complex with an h3k9me3 peptide and 2-oxoglutarate 1.8Å AUTH S.KRISHNAN,R.C.TRIEVELTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF JMJD2D REVEALSTITL 2 MOLECULAR BASIS FOR SITE-SPECIFIC DEMETHYLATION AMONG JMJD2TITL 3 DEMETHYLASES.REF STRUCTURE V. 21 98 2013REFN ISSN 0969-2126PMID 23219879DOI 10.1016/J.STR.2012.10.018 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2qlu ACVR2B crystal structure of activin receptor type ii kinase domain from human 2.0Å AUTH S.HAN,P.LOULAKIS,M.GRIFFOR,Z.XIETITL CRYSTAL STRUCTURE OF ACTIVIN RECEPTOR TYPE IIBTITL 2 KINASE DOMAIN FROM HUMAN AT 2.0 ANGSTROM RESOLUTIONREF PROTEIN SCI. V. 16 2272 2007REFN ISSN 0961-8368PMID 17893364DOI 10.1110/PS.073068407 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]