3AQG.B | ZG16B

General Structure Information

PDB ID	3aqg
HGNC Gene Label(s)	ZG16B
Structure Name	crystal structure of human pancreatic secretory protein zg16b
Resolution	2.75Å
Reference	AUTH M.KANAGAWA,T.SATOH,A.IKEDA,Y.NAKANO,H.YAGI,K.KATO,AUTH 2 K.KOJIMA-AIKAWA,Y.YAMAGUCHITITL CRYSTAL STRUCTURES OF HUMAN SECRETORY PROTEINS ZG16P ANDTITL 2 ZG16B REVEAL A JACALIN-RELATED BETA-PRISM FOLDREF BIOCHEM.BIOPHYS.RES.COMMUN. 2010REFN ESSN 1090-2104PMID 21110947DOI 10.1016/J.BBRC.2010.11.093

Variant Set Distributions

ExAC Variants

Number Of Residues	138
Number Of SNVs	47
Number Of Permutations	22649
Optimal Distance Threshold	12.0
K Statistic	0.278
p-value	0.0

Mapped Variants

[+] ExAC Missense Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
16:2880697		M>L	B:55	(-1.45, 9.53, -9.79)
16:2880699	rs369482276	M>I	B:55	(-1.45, 9.53, -9.79)
16:2880701		Y>C	B:56	(1.80, 9.76, -5.86)
16:2880706		P>S	B:58	(3.43, 2.44, -11.68)
16:2880712		G>R	B:60	(-2.39, 1.02, -15.02)
16:2880745	rs34779825	D>N	B:71	(-22.25, 16.57, 3.10)
16:2880761		G>V	B:76	(-13.34, 5.26, 7.90)
16:2880764		L>R	B:77	(-10.66, 3.34, 6.15)
16:2880767		R>L	B:78	(-13.67, -1.54, 5.49)
16:2880772	rs564514087	S>T	B:80	(-7.42, -5.26, 1.38)
16:2880775	rs375747814	V>I	B:81	(-3.53, -6.60, 2.73)
16:2880778		G>S	B:82	(-1.83, -9.76, 0.38)
16:2880782		L>P	B:83	(0.79, -11.68, 1.77)
16:2880785		L>H	B:84	(3.31, -9.35, -1.36)
16:2880796	rs368885459	S>G	B:88	(-8.60, -2.68, -1.51)
16:2880797		S>N	B:88	(-8.60, -2.68, -1.51)
16:2881798	rs571641627	V>I	B:89	(-9.39, 1.24, -0.82)
16:2881801	rs547452926	Q>E	B:90	(-14.21, 0.68, 1.81)
16:2881810		L>F	B:93	(-18.56, 8.79, 4.11)
16:2881828		V>M	B:99	(-17.77, 1.64, -2.96)
16:2881835		L>R	B:101	(-12.51, 1.19, -4.44)
16:2881838		G>A	B:102	(-10.64, -2.56, -6.85)
16:2881841		A>G	B:103	(-9.05, -5.59, -6.14)
16:2881846		G>S	B:105	(-8.96, -9.65, -1.99)
16:2881858	rs369515836	Q>K	B:109	(-7.28, -5.25, 7.99)
16:2881865	rs370286761	V>A	B:111	(-9.54, 1.82, 10.69)
16:2881871		L>P	B:113	(-11.54, 7.91, 12.21)
16:2881886		Y>C	B:118	(-10.37, 15.52, 10.90)
16:2881892	rs374921441	T>I	B:120	(-2.96, 15.11, 7.92)
16:2881898		V>G	B:122	(-0.53, 9.42, 3.12)
16:2881903		V>L	B:124	(2.56, 5.47, -0.66)
16:2881906	rs200978488	A>T	B:125	(4.50, 2.00, -1.27)
16:2881912	rs200195326 COSM3508419	Q>E	B:127	(6.94, -3.51, -5.22)
16:2881921	rs267604490	L>F	B:130	(0.27, -0.33, -3.16)
16:2881925		R>Q	B:131	(3.98, -4.07, 0.04)
16:2881928		G>V	B:132	(2.05, 0.44, 1.35)
16:2881930	rs35533993	M>V	B:133	(-1.23, 3.12, 2.96)
16:2881931	rs190229075	M>T	B:133	(-1.23, 3.12, 2.96)
16:2881933		V>I	B:134	(1.50, 5.17, 6.34)
16:2881955	rs377483530 COSM305438	R>H	B:141	(-4.91, 7.32, 15.89)
16:2881975		L>F	B:148	(6.59, 1.40, 3.74)
16:2881976	rs559867098	L>P	B:148	(6.59, 1.40, 3.74)
16:2881978		D>H	B:149	(8.96, -1.69, 0.55)
16:2881988		I>T	B:152	(8.51, 5.97, -0.54)
16:2881996		A>P	B:155	(0.56, 12.89, 0.74)
16:2882033	rs375406120	I>T	B:167	(-8.83, 7.84, -2.23)
16:2882035	rs370484892	Y>N	B:168	(-7.08, 9.88, -6.82)
16:2882048		Q>P	B:172	(-4.04, -4.21, -12.89)
16:2882059		I>L	B:176	(-3.58, -0.59, -6.18)
16:2882066	COSM3420920	S>N	B:178	(-2.04, 4.04, -8.94)
16:2882082	rs200324923 COSM3888334	W>C	B:183	(-5.46, 16.21, 0.82)