General Structure Information 4bkf EFNB3 crystal structure of the human epha4 ectodomain in complex with human ephrinb3 4.65Å AUTH E.SEIRADAKE,A.SCHAUPP,D.DEL TORO RUIZ,R.KAUFMANN,AUTH 2 N.MITAKIDIS,K.HARLOS,A.R.ARICESCU,R.KLEIN,E.Y.JONESTITL STRUCTURALLY ENCODED INTRACLASS DIFFERENCES IN EPHATITL 2 CLUSTERS DRIVE DISTINCT CELL RESPONSESREF NAT.STRUCT.MOL.BIOL. V. 20 958 2013REFN ISSN 1545-9993PMID 23812375DOI 10.1038/NSMB.2617 Variant Set Distributions Mapped Variants
General Structure Information 4cc1 JAG1 notch ligand, jagged-1, contains an n-terminal c2 domain 2.84Å AUTH C.R.CHILAKURI,D.SHEPPARD,M.X.G.ILAGAN,L.R.HOLT,F.ABBOTT,AUTH 2 S.LIANG,R.KOPAN,P.A.HANDFORD,S.M.LEATITL STRUCTURAL ANALYSIS UNCOVERS LIPID-BINDING PROPERTIES OFTITL 2 NOTCH LIGANDSREF CELL REP. V. 5 861 2013REFN ISSN 2211-1247PMID 24239355DOI 10.1016/J.CELREP.2013.10.029 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4cc1 JAG1 notch ligand, jagged-1, contains an n-terminal c2 domain 2.84Å AUTH C.R.CHILAKURI,D.SHEPPARD,M.X.G.ILAGAN,L.R.HOLT,F.ABBOTT,AUTH 2 S.LIANG,R.KOPAN,P.A.HANDFORD,S.M.LEATITL STRUCTURAL ANALYSIS UNCOVERS LIPID-BINDING PROPERTIES OFTITL 2 NOTCH LIGANDSREF CELL REP. V. 5 861 2013REFN ISSN 2211-1247PMID 24239355DOI 10.1016/J.CELREP.2013.10.029 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1toz NOTCH1 nmr structure of the human notch-1 ligand binding region -1.0Å AUTH S.HAMBLETON,N.V.VALEYEV,A.MURANYI,V.KNOTT,AUTH 2 J.M.WERNER,A.J.MCMICHAEL,P.A.HANDFORD,A.K.DOWNINGTITL STRUCTURAL AND FUNCTIONAL PROPERTIES OF THE HUMANTITL 2 NOTCH-1 LIGAND BINDING REGIONREF STRUCTURE V. 12 2173 2004REFN ISSN 0969-2126PMID 15576031DOI 10.1016/J.STR.2004.09.012 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1lmj FBN1 nmr study of the fibrillin-1 cbegf12-13 pair of ca2+ binding epidermal growth factor-like domains -1.0Å AUTH R.S.SMALLRIDGE,P.WHITEMAN,J.M.WERNER,I.D.CAMPBELL,AUTH 2 P.A.HANDFORD,A.K.DOWNINGTITL SOLUTION STRUCTURE AND DYNAMICS OF A CALCIUMTITL 2 BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAIN PAIRTITL 3 FROM THE NEONATAL REGION OF HUMAN FIBRILLIN-1.REF J.BIOL.CHEM. V. 278 12199 2003REFN ISSN 0021-9258PMID 12511552DOI 10.1074/JBC.M208266200 […]
General Structure Information 1yo8 THBS2 structure of the c-terminal domain of human thrombospondin-2 2.6Å AUTH C.B.CARLSON,D.A.BERNSTEIN,D.S.ANNIS,T.M.MISENHEIMER,AUTH 2 B.L.HANNAH,D.F.MOSHER,J.L.KECKTITL STRUCTURE OF THE CALCIUM-RICH SIGNATURE DOMAIN OF HUMANTITL 2 THROMBOSPONDIN-2REF NAT.STRUCT.MOL.BIOL. V. 12 910 2005REFN ISSN 1545-9993PMID 16186819DOI 10.1038/NSMB997 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1g1q SELP crystal structure of p-selectin lectin/egf domains 2.4Å AUTH W.S.SOMERS,J.TANG,G.D.SHAW,R.T.CAMPHAUSENTITL INSIGHTS INTO THE MOLECULAR BASIS OF LEUKOCYTETITL 2 TETHERING AND ROLLING REVEALED BY STRUCTURES OF P-TITL 3 AND E-SELECTIN BOUND TO SLE(X) AND PSGL-1.REF CELL(CAMBRIDGE,MASS.) V. 103 467 2000REFN ISSN 0092-8674PMID 11081633DOI 10.1016/S0092-8674(00)00138-0 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3cfw SELL l-selectin lectin and egf domains 2.2Å AUTH P.MEHTA,R.P.MCEVERTITL STRUCTURE OF LECTIN AND EGF DOMAINS OF L-SELECTINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2wcy C7 nmr solution structure of factor i-like modules of complement c7. -1.0Å AUTH M.M.PHELAN,C.T.THAI,D.C.SOARES,R.T.OGATA,AUTH 2 P.N.BARLOW,J.BRAMHAMTITL SOLUTION STRUCTURE OF FACTOR I-LIKE MODULES FROMTITL 2 COMPLEMENT C7 REVEALS A PAIR OF FOLLISTATINTITL 3 DOMAINS IN COMPACT PSEUDOSYMMETRIC ARRANGEMENT.REF J.BIOL.CHEM. V. 284 19637 2009REFN ISSN 0021-9258PMID 19419965DOI 10.1074/JBC.M901993200 Variant Set Distributions Ripley’s K […]
General Structure Information 4dg6 LRP6 crystal structure of domains 1 and 2 of lrp6 2.9Å AUTH G.HOLDSWORTH,P.SLOCOMBE,C.DOYLE,B.SWEENEY,V.VEVERKA,AUTH 2 K.LE RICH,R.J.FRANKLIN,D.BROOKINGS,J.TURNER,J.KENNEDY,AUTH 3 R.GARLISH,J.SHI,L.NEWNHAM,D.MCMILLAN,M.MUZYLAK,M.CARR,AUTH 4 A.J.HENRY,T.CESKA,M.K.ROBINSONTITL CHARACTERIZATION OF THE INTERACTION OF SCLEROSTIN WITH THETITL 2 LRP FAMILY OF WNT CO-RECEPTORSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]