General Structure Information
| PDB ID | 2wcy |
| HGNC Gene Label(s) | C7 |
| Structure Name | nmr solution structure of factor i-like modules of complement c7. |
| Resolution | -1.0Å |
| Reference | AUTH M.M.PHELAN,C.T.THAI,D.C.SOARES,R.T.OGATA,AUTH 2 P.N.BARLOW,J.BRAMHAMTITL SOLUTION STRUCTURE OF FACTOR I-LIKE MODULES FROMTITL 2 COMPLEMENT C7 REVEALS A PAIR OF FOLLISTATINTITL 3 DOMAINS IN COMPACT PSEUDOSYMMETRIC ARRANGEMENT.REF J.BIOL.CHEM. V. 284 19637 2009REFN ISSN 0021-9258PMID 19419965DOI 10.1074/JBC.M901993200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 151 |
| Number Of SNVs | 41 |
| Number Of Permutations | 18743 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.251 |
| p-value | 0.333 |
COSMIC
| Number Of Residues | 151 |
| Number Of SNVs | 5 |
| Number Of Permutations | 147 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.3 |
| p-value | 0.385 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 41 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.41 |
| p-value | 0.072 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
