Assessment of Structural Intolerance and Durability
General Structure Information 3swy CNGA3 cnga3 626-672 containing clz domain 1.9Å AUTH N.G.SHUART,Y.HAITIN,S.S.CAMP,K.D.BLACK,W.N.ZAGOTTATITL MOLECULAR MECHANISM FOR 3:1 SUBUNIT STOICHIOMETRY OF RODTITL 2 CYCLIC NUCLEOTIDE-GATED ION CHANNELS.REF NAT COMMUN V. 2 457 2011REFN ESSN 2041-1723PMID 21878911DOI 10.1038/NCOMMS1466 Variant Set Distributions Mapped Variants
General Structure Information 2da1 ZFHX3 solution structure of the first homeobox domain of at- binding transcription factor 1 (atbf1) -1.0Å AUTH S.OHNISHI,T.KIGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST HOMEOBOX DOMAIN OFTITL 2 AT-BINDING TRANSCRIPTION FACTOR 1 (ATBF1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wjr SFMBT2 solution structure of the 2nd mbt domain from human kiaa1617 protein -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 2ND MBT DOMAIN FROMTITL 2 HUMAN KIAA1617 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3bo5 SETMAR crystal structure of methyltransferase domain of human histone-lysine n-methyltransferase setmar 1.59Å AUTH H.WU,V.V.LUNIN,H.REN,E.DOBROVETSKY,J.WEIGELT,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,A.BOCHKAREV,J.MIN,A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAIN OF HUMANTITL 2 HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR IN COMPLEX WITHTITL 3 ADOHCY.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3vpp CLEC9A crystal structure of the human clec9a c-type lectin-like domain 1.64Å AUTH J.G.ZHANG,P.E.CZABOTAR,A.N.POLICHENI,I.CAMINSCHI,S.S.WAN,AUTH 2 S.KITSOULIS,K.M.TULLETT,A.Y.ROBIN,R.BRAMMANANTH,AUTH 3 M.F.VAN DELFT,J.LU,L.A.OREILLY,E.C.JOSEFSSON,B.T.KILE,AUTH 4 W.J.CHIN,J.D.MINTERN,M.A.OLSHINA,W.WONG,J.BAUM,M.D.WRIGHT,AUTH 5 D.C.HUANG,N.MOHANDAS,R.L.COPPEL,P.M.COLMAN,N.A.NICOLA,AUTH 6 K.SHORTMAN,M.H.LAHOUDTITL THE DENDRITIC CELL RECEPTOR CLEC9A BINDS DAMAGED CELLS VIATITL 2 EXPOSED ACTIN FILAMENTS.REF IMMUNITY V. 36 646 2012REFN ISSN 1074-7613PMID 22483802DOI 10.1016/J.IMMUNI.2012.03.009 Variant Set Distributions Mapped Variants
General Structure Information 3p53 FSCN1 structure of fascin 2.0Å AUTH S.JANSEN,A.COLLINS,C.YANG,G.REBOWSKI,T.SVITKINA,R.DOMINGUEZTITL MECHANISM OF ACTIN FILAMENT BUNDLING BY FASCIN.REF J.BIOL.CHEM. V. 286 30087 2011REFN ISSN 0021-9258PMID 21685497DOI 10.1074/JBC.M111.251439 Variant Set Distributions Mapped Variants
General Structure Information 2daj COBLL1 solution structure of the novel identified ubiquitin-like domain in the human cobl-like 1 protein -1.0Å AUTH C.ZHAO,T.KIGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE NOVEL IDENTIFIEDTITL 2 UBIQUITIN-LIKE DOMAIN IN THE HUMAN COBL-LIKE 1TITL 3 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wgx MIS18BP1 solution structure of rsgi ruh-022, a myb dna-binding domain in human cdna -1.0Å AUTH Y.DOI-KATAYAMA,H.HIROTA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-022, A MYBTITL 2 DNA-BINDING DOMAIN IN HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4h6j HIF1A identification of cys 255 in hif-1 as a novel site for development of covalent inhibitors of hif-1 /arnt pasb domain protein-protein interaction. 1.52Å AUTH R.CARDOSO,R.LOVE,C.L.NILSSON,S.BERGQVIST,D.NOWLIN,J.YAN,AUTH 2 K.K.LIU,J.ZHU,P.CHEN,Y.L.DENG,H.J.DYSON,M.J.GREIG,A.BROOUNTITL IDENTIFICATION OF CYS255 IN HIF-1 ALPHA AS A NOVEL SITE FORTITL 2 DEVELOPMENT OF COVALENT INHIBITORS OF HIF-1 ALPHA /ARNT PASBTITL 3 DOMAIN […]
General Structure Information 4iy3 CNNM4 structural and ligand binding properties of the bateman domain of human magnesium transporters cnnm2 and cnnm4 3.6Å AUTH M.A.CORRAL-RODRIGUEZ,M.STUIVER,J.A.ENCINAR,V.SPIWOK,AUTH 2 I.GOMEZ-GARCIA,I.OYENARTE,J.ERENO-ORBEA,H.TERASHIMA,AUTH 3 A.ACCARDI,T.DIERCKS,D.MULLER,L.A.MARTINEZ-CRUZTITL STRUCTURAL AND LIGAND BINDING PROPERTIES OF THE BATEMANTITL 2 DOMAIN OF HUMAN MAGNESIUM TRANSPORTERS CNNM2 AND CNNM4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants