General Structure Information
| PDB ID | 3bo5 |
| HGNC Gene Label(s) | SETMAR |
| Structure Name | crystal structure of methyltransferase domain of human histone-lysine n-methyltransferase setmar |
| Resolution | 1.59Å |
| Reference | AUTH H.WU,V.V.LUNIN,H.REN,E.DOBROVETSKY,J.WEIGELT,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,A.BOCHKAREV,J.MIN,A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAIN OF HUMANTITL 2 HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR IN COMPLEX WITHTITL 3 ADOHCY.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 269 |
| Number Of SNVs | 84 |
| Number Of Permutations | 39668 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.015 |
| p-value | 0.835 |
COSMIC
| Number Of Residues | 269 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 84 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | -0.32 |
| p-value | 0.616 |