Assessment of Structural Intolerance and Durability
General Structure Information 2ega SH3PXD2A solution structure of the first sh3 domain from human kiaa0418 protein -1.0Å AUTH K.INOUE,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST SH3 DOMAIN FROMTITL 2 HUMAN KIAA0418 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3lra LIN7C structural basis for assembling a human tripartite complex dlg1-mpp7- mals3 2.95Å AUTH X.YANG,X.XIE,L.CHEN,H.ZHOU,Z.WANG,W.ZHAO,R.TIAN,R.ZHANG,AUTH 2 C.TIAN,J.LONG,Y.SHENTITL STRUCTURAL BASIS FOR TANDEM L27 DOMAIN-MEDIATEDTITL 2 POLYMERIZATIONREF FASEB J. V. 24 4806 2010REFN ISSN 0892-6638PMID 20702775DOI 10.1096/FJ.10-163857 Variant Set Distributions Mapped Variants
General Structure Information 4e36 ERAP2 crystal structure of the human endoplasmic reticulum aminopeptidase 2 variant n392k 3.22Å AUTH I.EVNOUCHIDOU,J.BIRTLEY,S.SEREGIN,A.PAPAKYRIAKOU,E.ZERVOUDI,AUTH 2 M.SAMIOTAKI,G.PANAYOTOU,P.GIASTAS,O.PETRAKIS,D.GEORGIADIS,AUTH 3 A.AMALFITANO,E.SARIDAKIS,I.M.MAVRIDIS,E.STRATIKOSTITL A COMMON SINGLE NUCLEOTIDE POLYMORPHISM IN ENDOPLASMICTITL 2 RETICULUM AMINOPEPTIDASE 2 INDUCES A SPECIFICITY SWITCH THATTITL 3 LEADS TO ALTERED ANTIGEN PROCESSING.REF J.IMMUNOL. V. 189 2383 2012REFN ISSN 0022-1767PMID 22837489DOI 10.4049/JIMMUNOL.1200918 Variant […]
General Structure Information 1wf5 SDK2 solution structure of the first fn3 domain of sidekick-2 protein -1.0Å AUTH X.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST FN3 DOMAIN OFTITL 2 SIDEKICK-2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wig ABLIM2 solution structure of rsgi ruh-019, a lim domain of actin binding lim protein 2 (kiaa1808 protein) from human cdna -1.0Å AUTH T.ABE,H.HIROTA,S.KOSHIBA,T.KIGAWA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-019, A LIM DOMAINTITL 2 OF ACTIN BINDING LIM PROTEIN 2 (KIAA1808 PROTEIN)TITL 3 FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 1×68 FHL5 solution structures of the c-terminal lim domain of human fhl5 protein -1.0Å AUTH N.NAMEKI,A.SASAGAWA,M.SATO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C-TERMINAL LIM DOMAINTITL 2 OF HUMAN FHL5 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2e5s MBNL2 solution structure of the zf-ccchx2 domain of muscleblind- like 2, isoform 1 [homo sapiens] -1.0Å AUTH F.HE,W.DANG,C.ABE,K.TSUDA,M.INOUE,S.WATANABE,AUTH 2 N.KOBAYASHI,T.KIGAWA,T.MATSUDA,T.YABUKI,M.AOKI,AUTH 3 E.SEKI,T.HARADA,Y.TOMABECHI,T.TERADA,M.SHIROUZU,AUTH 4 A.TANAKA,P.GUNTERT,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA BINDING DOMAIN INTITL 2 THE HUMAN MUSCLEBLIND-LIKE PROTEIN 2REF PROTEIN SCI. V. 18 80 2009REFN ISSN 0961-8368PMID 19177353DOI 10.1002/PRO.17 Variant Set Distributions […]
General Structure Information 3dai ATAD2 crystal structure of the bromodomain of the human atad2 1.95Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Mapped Variants
General Structure Information 2cqk LARP4 solution structure of the la domain of c-mpl binding protein -1.0Å AUTH S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE LA DOMAIN OF C-MPLTITL 2 BINDING PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3bdl SND1 crystal structure of a truncated human tudor-sn 1.9Å AUTH C.L.LI,W.Z.YANG,Y.P.CHEN,H.S.YUANTITL STRUCTURAL AND FUNCTIONAL INSIGHTS INTO HUMANTITL 2 TUDOR-SN, A KEY COMPONENT LINKING RNA INTERFERENCETITL 3 AND EDITING.REF NUCLEIC ACIDS RES. V. 36 3579 2008REFN ISSN 0305-1048PMID 18453631DOI 10.1093/NAR/GKN236 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]