Assessment of Structural Intolerance and Durability
General Structure Information 1wy8 UHRF2 solution structure of the n-terminal ubiquitin-like domain in human np95/icbp90-like ring finger protein (nirf) -1.0Å AUTH C.ZHAO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINALTITL 2 UBIQUITIN-LIKE DOMAIN IN HUMAN NP95/ICBP90-LIKETITL 3 RING FINGER PROTEIN (NIRF)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4im6 NLRP1 lrr domain from human nlrp1 1.65Å Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2rep KIFC1 crystal structure of the motor domain of human kinesin family member c1 2.6Å AUTH H.ZHU,W.TEMPEL,H.HE,Y.SHEN,J.WANG,G.BROTHERS,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF HUMAN KINESINTITL 2 FAMILY MEMBER C1.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1v88 OSBPL8 solution structure of the pleckstrin homology domain of oxysterol-binding protein-related protein 8 (kiaa1451 protein) -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGYTITL 2 DOMAIN OF OXYSTEROL-BINDING PROTEIN-RELATEDTITL 3 PROTEIN 8 (KIAA1451 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yud YTHDC1 solution structure of the yth domain in yth domain- containing protein 1 (putative splicing factor yt521) -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TARADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTHTITL 2 DOMAIN-CONTAINING PROTEIN 1 (PUTATIVE SPLICINGTITL 3 FACTOR YT521)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3d34 SPON2 structure of the f-spondin domain of mindin 1.8Å AUTH Y.LI,C.CAO,W.JIA,L.YU,M.MO,Q.WANG,Y.HUANG,J.M.LIM,AUTH 2 M.ISHIHARA,L.WELLS,P.AZADI,H.ROBINSON,Y.W.HE,AUTH 3 L.ZHANG,R.A.MARIUZZATITL STRUCTURE OF THE F-SPONDIN DOMAIN OF MINDIN, ANTITL 2 INTEGRIN LIGAND AND PATTERN RECOGNITION MOLECULE.REF EMBO J. V. 28 286 2009REFN ISSN 0261-4189PMID 19153605DOI 10.1038/EMBOJ.2008.288 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2km6 NLRP7 nmr structure of the nlrp7 pyrin domain -1.0Å AUTH A.S.PINHEIRO,M.PROELL,C.EIBL,R.PAGE,R.SCHWARZENBACHER,W.PETITITL THREE-DIMENSIONAL STRUCTURE OF THE NLRP7 PYRIN DOMAIN:TITL 2 INSIGHT INTO PYRIN-PYRIN-MEDIATED EFFECTOR DOMAIN SIGNALINGTITL 3 IN INNATE IMMUNITY.REF J.BIOL.CHEM. V. 285 27402 2010REFN ISSN 0021-9258PMID 20547486DOI 10.1074/JBC.M110.113191 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2bk8 TTN m1 domain from titin 1.69Å AUTH S.MUELLER,I.KURSULA,M.WILMANNSTITL STRUCTURE OF M1 DOMAIN FROM TITINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3puc TTN atomic resolution structure of titin domain m7 0.96Å AUTH F.SAUER,M.WILMANNSTITL STRUCTURE OF TITIN M7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1g1c TTN i1 domain from titin 2.1Å AUTH O.MAYANS,J.WUERGES,S.CANELA,M.GAUTEL,M.WILMANNSTITL STRUCTURAL EVIDENCE FOR A POSSIBLE ROLE OFTITL 2 REVERSIBLE DISULPHIDE BRIDGE FORMATION IN THETITL 3 ELASTICITY OF THE MUSCLE PROTEIN TITIN.REF STRUCTURE V. 9 331 2001REFN ISSN 0969-2126PMID 11525170DOI 10.1016/S0969-2126(01)00591-3 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants