General Structure Information
| PDB ID | 1g1c |
| HGNC Gene Label(s) | TTN |
| Structure Name | i1 domain from titin |
| Resolution | 2.1Å |
| Reference | AUTH O.MAYANS,J.WUERGES,S.CANELA,M.GAUTEL,M.WILMANNSTITL STRUCTURAL EVIDENCE FOR A POSSIBLE ROLE OFTITL 2 REVERSIBLE DISULPHIDE BRIDGE FORMATION IN THETITL 3 ELASTICITY OF THE MUSCLE PROTEIN TITIN.REF STRUCTURE V. 9 331 2001REFN ISSN 0969-2126PMID 11525170DOI 10.1016/S0969-2126(01)00591-3 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 98 |
| Number Of SNVs | 31 |
| Number Of Permutations | 4044 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.396 |
| p-value | 0.392 |
COSMIC
| Number Of Residues | 98 |
| Number Of SNVs | 5 |
| Number Of Permutations | 64 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.2 |
| p-value | 0.897 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 31 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.275 |
| p-value | 0.767 |